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홈 > 분야별

의약학 > 정신과학 (8,162건)

Internet Addiction and Its Associations with Clinical and Psychosocial Factors in Medical Students
Internet Addiction and Its Associations with Clinical and Psychosocial Factors in Medical Students
Eun Hyun Seo;Seung-Gon Kim;Sang-Kyu Lee;Seon-Cheol Park;Hyung-Jun Yoon
대한신경정신의학회 / Psychiatry Investigation 제18권 제5호 / 2021 / 408-416 (9 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 정신과학
초록보기
Objective Excessive internet use has been associated with various psychiatric symptoms and psychosocial factors. This study aimed to investigate the prevalence of internet addiction (IA) and its associations with clinical (depression/social anxiety) and psychosocial (selfesteem/ perceived social support) factors in medical students. Methods In total, 408 medical students at one university in Korea were included in this study. IA symptoms were assessed with Young’s Internet Addiction Test, and scores of 50 or higher were considered to indicate IA. Participants were asked to complete the Beck Depression Inventory, Social Phobia Inventory, Rosenberg Self-Esteem Scale, and Duke-University of North Carolina Functional Social Support Questionnaire. A logistic regression model was constructed to examine the impact of clinical and psychosocial factors on IA. Results Forty-seven participants (11.5%) were identified as having IA. Self-esteem was associated with a lower risk of IA, whereas depression and social anxiety were associated with a higher risk of IA. Depression, social anxiety, low self-esteem, and low perceived social support were found to be significant correlates of IA. Young’s Internet Addiction Test score positively correlated with Beck Depression Inventory and Social Phobia Inventory scores, but negatively correlated with Rosenberg Self-Esteem Scale and Duke-University of North Carolina Functional Social Support Questionnaire scores. Furthermore, the prevalence of IA was highest in first-year medical students. Conclusion This study revealed the possible risk and protective factors of IA. Our findings indicate that strengthening self-esteem and reducing depression and social anxiety may contribute to the prevention and management of IA in medical students.
Functional Impairment in Patients with Panic Disorder
Functional Impairment in Patients with Panic Disorder
Hyun-Ju Kim;Ji Eun Kim;Sang-Hyuk Lee
대한신경정신의학회 / Psychiatry Investigation 제18권 제5호 / 2021 / 434-442 (9 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 정신과학
초록보기
Objective Anxiety and depression and sociodemographic factors such as age, gender, education level, income, and marital status among people with panic disorder (PD) are associated with functional impairment in the areas of work, social, and family. Although both PD-specific scales such as the Panic Disorder Severity Scale (PDSS) and Anxiety Sensitivity Inventory-Revised (ASI-R) and early trauma have been investigated, their relationship with functional impairment in PD patients has not been clarified. Methods This study included 267 PD patients. The PDSS, Beck Depression Inventory (BDI), ASI-R, and Early Trauma Inventory were used. Pearson’s correlation and multiple linear regression analyses were performed. The Sheehan Disability Scale (SDS) was administered to assess the functional impairment level in PD patients. Results Our findings showed that high levels of PDSS, BDI, and ASI-R were significantly correlated with the functional impairment among PD patients. Multiple regression analyses showed that PDSS, BDI, and ASI-R can predict the functional impairment levels, and PDSS and ASI-R were significantly associated with lost and underproductive days in PD patients. Conclusion Panic-specific symptoms, depression, and AS are associated with functional impairment level in PD patients. Elevated symptom severity can play a role by affecting productivity and daily responsibilities in PD patients.
읽기장애 개입프로그램의 효과성 개방형 연구
읽기장애 개입프로그램의 효과성 개방형 연구
유한익(Hanik K. Yoo);허한나(Hannah Huh);조민지(Minji Jo);이현주(Hyunju Lee);홍인화(In-Hwa Hong);김중훈(Jung Hun Kim);양수진(Su-Jin Yang);정재석(Jaesuk Jung)
대한신경정신의학회 / 신경정신의학 제60권 제2호 / 2021 / 126-134 (9 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 신경과학
초록보기
본 연구에서는 읽기장애로 진단된 학령기 아동들을 대상으로 일선 교사들이 학교 현장에서 읽기장애 개입을 시도하고 그 효과성을 검증하고자 하였다. 그 결과, 단어 수준의 읽기 정확성과 유창성이 향상되었으며, 이런 현상은 난독형에서 가장 두드러졌다. 반면 읽기장애 이해형에서는 개입 효과가 관찰되지 않았다.
Swedish Universities Scales of Personality
Swedish Universities Scales of Personality
Tomas Fagerberg;Erik Söderman;J Petter Gustavsson;Ingrid Agartz;Erik G Jönsson
대한신경정신의학회 / Psychiatry Investigation 제18권 제5호 / 2021 / 373-384 (12 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 정신과학
초록보기
Objective To investigate associations between Swedish universities Scales of Personality (SSP) and scales of the following personality instruments: Structured Clinical Interview for DSM-III-R axis II screening questionnaire (SCID-II screen), revised NEO personality inventory (NEO-PI-R), revised Chapman scales (Chapman) and the psychotic traits questionnaire (STQ). Methods Healthy individuals (n=406) completed self-report personality questionnaires including SSP and at least one more personality inventory. Correlations were calculated between the 13 different SSP subscales as well as SSP’s three factors and factors and scales/subscales in SCID-II screen, NEO-PI-R, Chapman and STQ. The main factors of the various instruments were factor analysed. ICC were calculated. Results SSP Neuroticism factor correlated with SCID-II cluster C (r=0.71), NEO Neuroticism (r=0.80) and Chapman Social anhedonia (r=0.62). SSP Extraversion factor correlated with NEO Extraversion (r=0.63) and SSP Aggressiveness factor with NEO Agreeableness (r=-0.62). Strong correlations between SSP factors and scales and scales of the other instruments were sparse, although weaker correlations were common. Conclusion SSP is a useful investigation tool when measuring personality traits related to temperament-like features. SSP partly correlates well to especially three of the NEO-PI-R factors. The different personality inventories are not completely comparable to each other. Instead, they measure personality aspects in partly different ways.
Association of Sleep Duration and Working Hours with Suicidal Ideation in Shift Workers
Association of Sleep Duration and Working Hours with Suicidal Ideation in Shift Workers
Sun-Young Kim;Soo In Kim;Weon-Jeong Lim
대한신경정신의학회 / Psychiatry Investigation 제18권 제5호 / 2021 / 400-407 (8 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 정신과학
초록보기
Objective This study investigated whether sleep duration and working hours were associated with the risk of suicidal ideation. Methods Data from 13,628 shift workers (age ≥19) were obtained from the nationwide cross-sectional Korea National Health and Nutrition Examination Surveys conducted in 2007–2018. We included healthy shift workers without depressive disorders and chronic medical illnesses. Sleep duration, working hours, and suicidal ideation were assessed using a self-reported questionnaire. Logistic regressions were used to examine the association of sleep duration and working hours with the risk of suicidal ideation. We examined interactions between sleep duration and working hours in association with suicidal ideation. In addition, interactions of sex or age were also analyzed. Results Shift workers sleeping for <6 and ≥10 hours/day were associated with suicidal ideation compared with those sleeping for 7 to <9 hours/day. Individuals working >52 hours/week had a higher risk of suicidal ideation compared with those working ≤40 hours/week. In terms of interaction by sex or age groups in the association between working hours and the risk of suicidal ideation, the relationship was stronger for men than for women and for those aged <45 years than for those aged ≥45 years. Conclusion Shorter or longer sleep durations, and long working hours were associated with a higher risk of suicidal ideation. Under long working hours, male shift workers or those aged <45 years were more vulnerable to suicidal ideation.
The Prevalence of Post-Traumatic Stress Disorder in the General Population during the COVID-19 Pandemic
The Prevalence of Post-Traumatic Stress Disorder in the General Population during the COVID-19 Pandemic
Liqing Zhang;Rong Pan;Yixian Cai;Jiyang Pan
대한신경정신의학회 / Psychiatry Investigation 제18권 제5호 / 2021 / 426-433 (8 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 정신과학
초록보기
Objective To investigate the prevalence of post-traumatic stress disorder (PTSD) in the general population during the COVID-19 pandemic by a systematic review and single-arm meta-analysis. Methods CNKI, PubMed, EMBASE, and MEDLINE were searched to collect literature on the prevalence of PTSD in the general population during the epidemic. The retrieval time is from the database construction to 31/08/2020. Meta-analysis was performed on the included articles by using Review Manger 5.3 and Stata 16.0 software. Results The prevalence of PTSD in the general population during the COVID-19 pandemic was 15% (95% CI: 11–21%, p<0.001). Conclusion The COVID-19 pandemic brought certain mental pain to general population, leading to a rise in the incidence of PTSD in a short time.
성범죄를 저지른 소아성애자의 임상적 특징
성범죄를 저지른 소아성애자의 임상적 특징
문지용(Ji-Yong Moon);임경옥(Kyung-Ok Lim);조성남(Seongnam Cho);장소영(Soyeong Jang);차승민(Seung-Min Cha);한송이(Songyi Han)
대한신경정신의학회 / 신경정신의학 제60권 제2호 / 2021 / 120-125 (6 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 신경과학
초록보기
본 연구는 성범죄를 저지른 변태성욕장애 환자들의 임상적 특징을 알아보고 소아성애장애의 혈중 테스토스테론 농도와 지적장애 동반 유무에 대해 알아본 국내 첫 연구로 치료감호 3호 판결을 받은 변태성욕장애 환자들 중에서 소아성애장애가 제일 많았고, 소아성애장애 환자들은 혈중 테스토스테론 농도가 낮았으며 지적장애가 많이 동반되었다. 본 연구 결과는 몇몇 제한점으로, 보다 많은 대상자를 포함하는 전향적 추적연구와 같은 추가 연구와 반복 검증이 필요할 것으로 생각되지만, 소아성애장애 환자의 특징을 이해하는 기초자료로 활용을 기대한다. 소아성범죄의 예방과 치료에 대한 적절한 임상적 활용을 위해 다양한 후속연구를 통해 소아성애장애의 병태생리를 밝히려는 노력이 지속되어야 한다.
Association between the Arylalkylamine N-Acetyltransferase (AANAT) Gene and Seasonality in Patients with Bipolar Disorder
Association between the Arylalkylamine N-Acetyltransferase (AANAT) Gene and Seasonality in Patients with Bipolar Disorder
So Yung Yang;Kyung Sue Hong;Youngah Cho;Eun-Young Cho;Yujin Choi;Yongkang Kim;Taesung Park;Kyooseob Ha;Ji Hyun Baek
대한신경정신의학회 / Psychiatry Investigation 제18권 제5호 / 2021 / 453-464 (12 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 정신과학
초록보기
Objective Bipolar disorder (BD) is complex genetic disorder. Therefore, approaches using clinical phenotypes such as biological rhythm disruption could be an alternative. In this study, we explored the relationship between melatonin pathway genes with circadian and seasonal rhythms of BD. Methods We recruited clinically stable patients with BD (n=324). We measured the seasonal variation of mood and behavior (seasonality), and circadian preference, on a lifetime basis. We analyzed 34 variants in four genes (MTNR1a, MTNR1b, AANAT, ASMT) involved in the melatonin pathway. Results Four variants were nominally associated with seasonality and circadian preference. After multiple test corrections, the rs116879618 in AANAT remained significantly associated with seasonality (corrected p=0.0151). When analyzing additional variants of AANAT through imputation, the rs117849139, rs77121614 and rs28936679 (corrected p=0.0086, 0.0154, and 0.0092) also showed a significant association with seasonality. Conclusion This is the first study reporting the relationship between variants of AANAT and seasonality in patients with BD. Since AANAT controls the level of melatonin production in accordance with light and darkness, this study suggests that melatonin may be involved in the pathogenesis of BD, which frequently shows a seasonality of behaviors and symptom manifestations.
우울증상 및 정신건강 보호-취약요인 선별평가를 위한 배터리 평가도구의 개발
우울증상 및 정신건강 보호-취약요인 선별평가를 위한 배터리 평가도구의 개발
이주열(Ju-Yeal Lee);최선우(Sun-Woo Choi);장수아(Soo-Ah Jang);류진선(Jin-Sun Ryu);신현경(Hyun-Kyung Shin);심재윤(Jae-Yun Sim);석정호(Jeong-Ho Seok)
대한신경정신의학회 / 신경정신의학 제60권 제2호 / 2021 / 143-157 (15 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 신경과학
초록보기
이 연구 결과, 우울증상 뿐 아니라 그에 대한 보호-취약 요인을 통합적으로 평가할 수 있는 PROVE 평가도구가 개발되었고, PROVE의 5가지 하위 영역들 모두 비교적 높은 내적 합치도 및 타당도를 보여 타당한 측정 도구로 평가되었다. 각 하위 영역들은 기존의 척도들과 비교했을 때 좀 더 세세한 항목들을 추가해서 평가한다는 강점이 있고, 검사 항목들 간 상관관계도 유의미하여 유기적으로 잘 연결된 하나의 배터리로 개발되었다. 이 평가도구는 정신건강 선별 과정에 있어 우울증에 대한 심층적, 다면적 이해를 높이고, 더 나아가 우울증의 예방이나 평가, 진단, 치료 과정에 유용하게 이용될 것으로 예상된다.
Effects of Organic Light-Emitting Diodes on Circadian Rhythm and Sleep
Effects of Organic Light-Emitting Diodes on Circadian Rhythm and Sleep
Hyunjin Jo;Hea Ree Park;Su Jung Choi;Soo-Youn Lee;Seog Ju Kim;Eun Yeon Joo
대한신경정신의학회 / Psychiatry Investigation 제18권 제5호 / 2021 / 471-478 (8 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 정신과학
초록보기
Objective Organic light-emitting diodes (OLEDs) emit less blue light than traditional light-emitting diodes (LEDs), and we previously found that early-night OLED light exposure (LE) delays the melatonin phase by less than LED at a color temperature of 4,000 K. As a follow-up study, we investigated the effects of OLED and LED at a different color temperature (3,000 K) on melatonin profile, sleep, and vigilance. Methods 24 healthy subjects (27.5±5.1 years) were exposed to three light conditions [OLED, LED, and dim light (DL)] from 17:30 to 24:00, in a random order and with a 1-week interval. Saliva samples for melatonin were taken every hour from 18:00 to 24:00. Polysomnography (PSG) and a psychomotor vigilance test (PVT) were performed. Results Melatonin onset time was significantly delayed under OLED and LED compared with DL, with no significant difference between OLED and LED. The mean melatonin level at 24:00 under LED was lower than that under DL, but there was no significant difference between OLED LE and DL. The percentage of slow wave sleep (N3) in LED was significantly lower than in OLED. Conclusion Exposure to light in the evening can suppress melatonin secretion late at night and disturb deep sleep, and those effects are slightly worse under LED than OLED.
The Role of Event-Related Rumination and Perceived Social Support on Psychological Distress during the COVID-19 Pandemic
The Role of Event-Related Rumination and Perceived Social Support on Psychological Distress during the COVID-19 Pandemic
Hyo Shin Kang;Bin-Na Kim
대한신경정신의학회 / Psychiatry Investigation 제18권 제5호 / 2021 / 392-399 (8 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 정신과학
초록보기
factors that can exacerbate or mitigate such distress have remained underexplored. To address the research gap, this study examined whether two types of rumination and perceived social support predict psychological distress during the pandemic. Methods Participants were recruited from communities of the greater Daegu area (n=316) where the first massive outbreak in South Korea occurred and most residents underwent substantial disruption of daily life. They completed self-report questionnaires that included measures of psychological distress, event-related rumination, and social support. Results The hierarchical regression analysis showed that maladaptive intrusive rumination and perceived social support predicted increases and decreases in psychological distress, respectively, even when subjective severity of COVID-19-related experiences was controlled. Putatively adaptive type of rumination (i.e., deliberate rumination) was not a significant predictor concurrently. Conclusion This is among the early endeavors to comprehensively understand risk and protective factors associated with an effective coping strategy against the COVID-19 crisis. Our results indicate that intrusive rumination aggravates but social support mitigates psychological distress during the pandemic, indicating that we can better adapt by differently attending to recent experiences and maintaining perceived social support.
The Prediction Analysis of Autistic and Schizotypal Traits in Attentional Networks
The Prediction Analysis of Autistic and Schizotypal Traits in Attentional Networks
Wanling Huang;Long Zhang;Yaoting Sun;Fangfang Chen;Kai Wang
대한신경정신의학회 / Psychiatry Investigation 제18권 제5호 / 2021 / 417-425 (9 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 정신과학
초록보기
Objective Empirical findings confirmed that autistic and schizotypal traits are associated with attentional function as well as include various dimensions. So far, no study has reported which dimension of these traits relates to attentional networks. This study aimed to find out whether there are associations between attentional networks and autistic traits; and between attentional networks and schizotypal traits. Methods A total of 449 volunteers was included in this study, and autism-spectrum quotient (AQ), schizotypal personality questionnaire (SPQ), and attention network test (ANT) were used to measure autistic traits and schizotypal traits. The three independent attentional networks, including alerting network, orienting network, and executive control network, were also measured. Results Autistic traits were associated with the orienting network, whereas schizotypal traits were associated with the orienting network and executive control network. Furthermore, attentional networks could be predicted by specific dimensions of autistic and schizotypal traits. AQ-attention switching [0.104 (-1.175– -0.025), p=0.041] and AQ-attention to detail [-0.097 (-0.798– -0.001), p=0.049] were significant predictors of orienting network and gender were significant predictor of executive network (Beta=0.107; 95% CI=-0.476–10.139; p=0.031). Whereas, schizotypal dimension “interpersonal” was a significant predictor of all three attentional networks [Alerting: 0.147 (-0.010–0.861), p=0.045; Orienting: 0.147 (0.018–0.733), p=0.040; Executive: 0.198 (0.215–1.309), p=0.006]. Conclusion This study demonstrated that autistic and schizotypal traits were associated with attentional networks. The specific dimensions of autistic and schizotypal traits could predict attentional networks. Nevertheless, the attentional networks predicted with these two traits were different.
The Relationship between Coronavirus Anxiety, Mindfulness and Spiritual Health in Patients with Cancer
The Relationship between Coronavirus Anxiety, Mindfulness and Spiritual Health in Patients with Cancer
Mahlagha Dehghan;Zakieh Namjoo;Ahmad Zarei;Hanieh Tajedini;Amir Bahrami;Mohammad Ali Zakeri
대한신경정신의학회 / Psychiatry Investigation 제18권 제5호 / 2021 / 443-452 (10 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 정신과학
초록보기
Objective The sudden outbreak of COVID-19 has caused major health problems, including anxiety in cancer patients worldwide. Spiritual health and mindfulness are considered as factors affecting anxiety. This study addressed the relationship between COVID-19 anxiety, spiritual health and mindfulness in patients with cancer. Methods One hundred and eighty-four cancer patients participated in this cross-sectional study. The data were collected with convenience sampling method from two oncology centers from 15 June to 15 July 2020 in the southeast Iran. Patients completed the Demographic and Clinical Characteristics Form, Corona Disease Anxiety Scale (CDAS), The Freiburg Mindfulness inventory-Short Form (FMI-SF) and Spiritual Health Scale. Results According to the psychological symptom subscale (CDAS), 61.4% of the participants had moderate to severe anxiety. According to the physical symptom subscale, 38% of the participants had moderate to severe anxiety. No significant association was found between corona disease anxiety and mindfulness/spiritual health (p>0.05). Conclusion The results of this study showed high levels of mental and physical anxiety and worries about COVID-19 disease in cancer patients, which led to challenges in their lives. It is necessary to review and implement effective interventions in future studies to prevent anxiety and its consequences in cancer patients.
현대 정신의학에서 바라본 반 고흐의 정신세계와 정신질환에 대한 고찰
현대 정신의학에서 바라본 반 고흐의 정신세계와 정신질환에 대한 고찰
이영식(Young Sik Lee)
대한신경정신의학회 / 신경정신의학 제60권 제2호 / 2021 / 97-119 (23 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 신경과학
초록보기
빈센트 반 고흐는 1890년 7월 말 자살로 생을 마감한지 130년이 지난 현 시점에서도 그의 드라마틱한 삶의 여정과, 정신질환, 무엇보다도 예술적 천재성에 사람들은 매료되어, 그간 200명이 넘는 의사들이 각자 자기 전문의학 분야의 입장에서 30여 개의 진단을 제안하고 구체적 새로운 증거자료들을 지속적으로 제출하고 있다. 측두엽 간질, 메니어씨병, 포르피리아, 3기매독, 압생트 남용, 알코올 중독, 유기용매제중독, 납중독, 디지털리스 중독, 녹내장, 백내장 등이 신체질환으로 제기되었다. 정신질환으로는 경계성인격장애, 우울조증을 동반한 기분장애, 조현병이 있다. 본고에서는 보다 객관적이고 통합적인 정보를 통해 진실에 접근하고자 빈센트의 삶의 여정, 편지, 담당의사들의 기록, 빈센트 자신의 병식, 주변인들의 진술, 가족력 등에 대해 정리하였고, 제기된 여러 질병들에 관한 근거와 논쟁점에 대해 정리하였다. 이를 요약하면 빈센트의 병전 성격은 경계성인격장애로 주변인들과의 갈등이 지속적으로 초래되었고, 긴 우울삽화 후 이어지는 경조증은 전 생애에 걸쳐 여러 번 있었다는 것이다. 때로는 기억상실을 동반하며 주기적으로 발생한 환청, 환시, 피해망상, 종교망상, 자해행동에 대한 진단으로 측두엽 간질은 빈센트 시대 이래 현재까지 주진단으로 계속 제기되고 있으며, 20세기 말 들어서 조증 경조증에 대한 개념이 확장되면서 양극성정동장애, 조현기분장애 또한 주진단으로 인정되는 추세이다. 정신 증상의 악화 요인은 테오로부터 격리 불안을 유발하는 일련의 생활 사건(고갱과의 결별, 테오의 약혼, 결혼, 자녀출생, 양육 스트레스)들과 압생트를 포함한 뇌 독성 물질남용이라고 하겠다. 빈센트의 정신증상을 단일 질환으로 설명하기에는 무리가 따르지만, 빈센트의 가장 우선시되는 진단을 언급하라면 양극성장애 특성과 조현병 특성을 동시에 보이는 조현정동장애 양극성형이라 하겠다.
Using Prazosin to Treat Posttraumatic Stress Disorder and Associations: A Systematic Review
Using Prazosin to Treat Posttraumatic Stress Disorder and Associations: A Systematic Review
Henrique Soares Paiva;Idiberto José Zotarelli Filho;Carlos Filinto da Silva Cais
대한신경정신의학회 / Psychiatry Investigation 제18권 제5호 / 2021 / 365-372 (8 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 정신과학
초록보기
Objective A central adrenergic hyperactivation is described in the neurobiology of posttraumatic stress disorder (PTSD) with probable variable symptomatic impact. Few studies have evaluated using the alpha-1 adrenergic antagonist prazosin for such symptoms; however, given the likely pathophysiology involved, this drug may play an important role in the pharmacological approach to PTSD. Methods This study assessed articles already published on the use of prazosin through a systematic review along a timeline in view of the symptomatic target of difficult access by standardized treatments. The impact of using this medication for the general symptoms of PTSD is also discussed. Several databases were searched for articles in the literature on the use of prazosin to treat PTSD. Results A total of 168 articles were found containing search terms in the title or abstract. Overall, 85 articles met the criteria described, and 48 studies were explored to conduct the present systematic review. Most articles showed some improvement after prazosin administration, especially in relation to sleep symptoms (nightmares and night waking). Only one article demonstrated no improvement after the use of this drug. More randomized studies are needed. Conclusion Several clinical studies demonstrated the relevant role of prazosin for treating PTSD symptoms. Prazosin is an affordable and cost-effective pharmacological option compared to other drugs used to treat PTSD.
Psychological Factors Associated with Social Withdrawal (Hikikomori)
Psychological Factors Associated with Social Withdrawal (Hikikomori)
Shunsuke Nonaka;Motohiro Sakai
대한신경정신의학회 / Psychiatry Investigation 제18권 제5호 / 2021 / 463-471 (9 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 정신과학
초록보기
Objective Cases of prolonged social withdrawal (hikikomori) have recently been reported in several countries. This study examined the impact of cognitive-behavioral and emotional factors on hikikomori behavior to identify intervention targets. Identifying such targets could facilitate the development of techniques to address hikikomori characteristics. Methods Two hundred Japanese individuals (mean age=38.73, SD=6.85) completed the Adaptive Behaviors Scale for Hikikomori and Stress Response Scale-18, along with the Japanese versions of the Self-Compassion Scale (Short Form), Acceptance and Action Questionnaire- II, and Brief Coping Orientation to Problems Experienced Inventory. Participants were divided into two groups: individuals with no experience of social withdrawal, and those with experience of social withdrawal. Results Hierarchical multiple regression analysis showed that the use of instrumental support, behavioral disengagement stress coping skills, self-compassion, and psychological stress were associated with hikikomori behaviors. Furthermore, higher instrumental support levels, associated with a decrease in hikikomori behaviors, were found in the hikikomori group. Conclusion The use of instrumental support, behavioral disengagement stress coping skills, self-compassion, and psychological stress should be targeted in hikikomori prevention interventions. Moreover, encouragement for the use of instrumental support is needed for improving hikikomori.
전기경련치료에 대한 환자의 만족도 조사
전기경련치료에 대한 환자의 만족도 조사
주은정(Eun-Jeong Joo);김희철(Hee Cheol Kim);정성훈(Seong Hoon Jeong);박승현(Seung Hyun Park);이남영(Nam Young Lee);최영숙(Young Sook Choi);김용식(Yong Sik Kim);정인원(In Won Chung)
대한신경정신의학회 / 신경정신의학 제60권 제2호 / 2021 / 135-142 (8 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 신경과학
초록보기
전기경련치료에 대한 환자의 인식과 태도를 파악하고자 설문 조사를 실시한 결과, 많은 환자들이 전기경련치료에 대한 만족도 및 부작용, 태도, 경험 등에서 대체로 긍정적인 응답을 하였다. 응답자 중에서 반수 이상이 전기경련치료 동안에 기억장애를 경험하였다. 본 연구에서는 전기경련치료의 만족도에 직접적으로 영향을 미치는 예측 요인을 확인하지는 못하였으나 전기경련치료 동안에 발생하는 일시적인 부작용들과 기억장애에 대한 예방, 조기 발견과 신속한 처치가 필요한 것을 알 수 있었다. 후속 연구에서 대상자 수의 확대와 다양한 변인들을 탐색함으로써 전기경련치료의 만족도를 높일 수 있는 예측 요인들을 규명할 수 있을 것으로 판단된다.
Transcriptome Sequencing Reveals the Potential Mechanisms of Modified Electroconvulsive Therapy in Schizophrenia
Transcriptome Sequencing Reveals the Potential Mechanisms of Modified Electroconvulsive Therapy in Schizophrenia
Wanhong Peng;Qingyu Tan;Minglan Yu;Ping Wang;Tingting Wang;Jixiang Yuan;Dongmei Liu;Dechao Chen;Chaohua Huang;Youguo Tan;Kezhi Liu;Bo Xiang;Xuemei Liang
대한신경정신의학회 / Psychiatry Investigation 제18권 제5호 / 2021 / 385-396 (12 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 정신과학
초록보기
Objective Schizophrenia (SCZ) is one of the most common and severe mental disorders. Modified electroconvulsive therapy (MECT) is the most effective therapy for all kinds of SCZ, and the underlying molecular mechanism remains unclear. This study is aim to detect the molecule mechanism by constructing the transcriptome dataset from SCZ patients treated with MECT and health controls (HCs). Methods Transcriptome sequencing was performed on blood samples of 8 SCZ (BECT: before MECT; AECT: after MECT) and 8 HCs, weighted gene co-expression network analysis (WGCNA) was used to cluster the different expression genes, enrichment and protein-protein interaction (PPI) enrichment analysis were used to detect the related pathways. Results Three gene modules (black, blue and turquoise) were significantly associated with MECT, enrichment analysis found that the long-term potentiation pathway was associated with MECT. PPI enrichment p-value of black, blue, turquoise module are 0.00127, <1×10-16 and 1.09×10-13, respectively. At the same time, EP300 is a key node in the PPI for genes in black module, which got from the transcriptome sequencing data. Conclusion It is suggested that the long-term potentiation pathways were associated with biological mechanism of MECT.
Resilience and Work-Related Stress May Affect Depressive Symptoms in Nursing Professionals during the COVID-19 Pandemic Era
Resilience and Work-Related Stress May Affect Depressive Symptoms in Nursing Professionals during the COVID-19 Pandemic Era
Youjin Hong;Jukab Lee;Hyuk Joo Lee;Kyumin Kim;Inn-Kyu Cho;Myung Hee Ahn;Yong-Wook Shin;Jangho Park;Seockhoon Chung
대한신경정신의학회 / Psychiatry Investigation 제18권 제4호 / 2021 / 357-363 (7 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 정신과학
초록보기
Objective We aimed to investigate the effect of nursing professionals’ resilience on their mental health, work-related stress, and anxiety in response to the COVID-19 pandemic. Methods We conducted an online survey in the Asan Medical Center and Ulsan University Hospital, South Korea. We extracted data of 824 nursing professionals who consented to participate, including demographic variables and the Stress and Anxiety to Viral Epidem-ics-9 (SAVE-9), PHQ-9, GAD-7, and Brief Resilience Scale scores. Results Resilience was negatively correlated with Patient Health Questionnaire-9 (PHQ-9) (rho=-0.23), Generalized Anxiety Scale-7 items (GAD-7) (rho=-0.25), Stress and Anxiety to Viral Epidem-ics-6 items (SAVE-6) (rho=-0.15), and Stress And anxiety to Viral Epidem-ics-3 items (SAVE-3) (rho=-0.13, all, p<0.001). Logistic regression analysis adjusting age, marital status, and years of employment revealed that high level of general anxiety [adjusted odds ratio (aOR)=1.40, 95% confidence interval (CI)=1.31–1.50], work-related stress during viral epidemics (aOR=1.16, 95% CI=1.03–1.29), and a low level of resilience (aOR=0.91, 95% CI=0.85–0.97) were expecting variables for the depression of healthcare workers. Conclusion Nursing professionals’ level of resilience may be associated with low level of work-related stress and anxiety induced by a viral epidemic. We need to explore further the possibility of resilience as coping strategy of healthcare workers in this pandemic era. Psychiatry Investig 2021;18(4):357-363
The Burden of Agoraphobia in Worsening Quality of Life in a Community Survey in Italy
The Burden of Agoraphobia in Worsening Quality of Life in a Community Survey in Italy
Antonio Preti;Martina Piras;Giulia Cossu;Elisa Pintus;Mirra Pintus;Goce Kalcev;Federico Cabras;Maria Francesca Moro;Ferdinando Romano;Matteo Balestrieri;Filippo Caraci;Liliana Dell’Osso;Guido Di Sciascio;Filippo Drago;Maria Carolina Hardoy;Rita Roncone;Carlo Faravelli;Mario Musu;Gabriele Finco;Antonio Egidio Nardi;Mauro Giovanni Carta
대한신경정신의학회 / Psychiatry Investigation 제18권 제4호 / 2021 / 277-283 (7 pages)
의약학>정신과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 정신과학
초록보기
Objective Current nosology redefined agoraphobia as an autonomous diagnosis distinct from panic disorder. We investigated the life-time prevalence of agoraphobia, its association with other mental disorders, and its impact on the health-related quality of life (HR-QoL). Methods Community survey in 2,338 randomly selected adult subjects. Participants were interviewed with the Advanced Neuropsy-chiatric Tools and Assessment Schedule (ANTAS), administered by clinicians. The diagnoses were based on the ICD-10 criteria. The Short-Form Health Survey (SF-12) was used to quantify HR-QoL. Results In the sample, 35 subjects met the criteria for agoraphobia (1.5%), with greater prevalence among women (2.0%) than men (0.9%): odds ratio (OR) 2.23; 95% CI: 1.0-5–2. Agoraphobia was more often seen among those with (n=26; 1.1%) than without (n=9; 0.4%) panic disorder: OR=8.3; 2.9–24.4. Co-morbidity with other mental disorders was substantial. The mean score of SF-12 in people with agoraphobia was 35.2±7.8, with similar levels of HR-QoL in people with (35.3±7.9) or without (34.8±7.3) panic disorder: ANOVA: F(1;33)=0.0; p=1.00. Conclusion One out of seventy people may suffer from agoraphobia in their lifetime. The attributable burden in terms of HR-QoL is substantial and comparable to the one observed for chronic mental disorders such as major depression, post-traumatic stress disorder, or obsessive-compulsive disorder. Psychiatry Investig 2021;18(4):277-283