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In the present study, we investigated the effect of oncogenic H-Ras on rat mdr1b expression in NIH3T3 cells. The constitutive expression of H-RasV12 was found to downregulate the mdr1b promoter activi...
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DISCUSSION
ㆍInhibition of chromosomal region maintenance 1 suppresses the migration and invasion of glioma cells via inactivation of the STAT3/MMP2 signaling pathway
ㆍInteraction of promyelocytic leukemia/p53 affects signal transducer and activator of transcription-3 activity in response to oncostatin M
ㆍSalvianolic acid B ameliorates psoriatic changes in imiquimodinduced psoriasis on BALB/c mice by inhibiting inflammatory and keratin markers via altering phosphatidylinositol-3-kinase/ protein kinase B signaling pathway
ㆍSesamin induces A549 cell mitophagy and mitochondrial apoptosis via a reactive oxygen species-mediated reduction in mitochondrial membrane potential
ㆍATG5 knockout promotes paclitaxel sensitivity in drug-resistant cells via induction of necrotic cell death
ㆍHeat shock protein 90 inhibitor AUY922 attenuates platelet-derived growth factor-BB-induced migration and proliferation of vascular smooth muscle cells
ㆍOxysterol 25-hydroxycholesterol as a metabolic pathophysiological factors of osteoarthritis induces apoptosis in primary rat chondrocytes
ㆍD-Limonene mitigate myocardial injury in rats through MAPK/ ERK/NF-κB pathway inhibition
ㆍOncogenic Ras downregulates mdr1b expression through generation of reactive oxygen species
ㆍCa2+/calmodulin-dependent regulation of polycystic kidney disease 2-like-1 by binding at C-terminal domain
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