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상피세포성장인자(rhEGF) DWP401의 랫드에서의 수태능 및 일반생식독성에 관한 연구

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상피세포성장인자(rhEGF) DWP401의 랫드에서의 수태능 및 일반생식독성에 관한 연구
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선인장의 약리활성 탐색
Effects of asiaticoside derivatives on wound healing
Asiatic acid 유도체의 창상치유 효과에 관한 연구
Enhanced motility of wounded endothelial cells by histamine
Expression of human M1 and M2 muscarinic acetylcholine receptor subtypes in a baculovirus expression system
신규 복합제산인 GFM2의 효력시험 연구
신규 복합제산인 GFM2의 일반약리작용
급성간질환모델에 있어 인진호 다당체분획(PS-1)의 용량반응성에 관한 연구
Synthesis and biological evaluation of bioisosteric analogs of phentolamine
Synthesis and in vitro evaluation of 3-substituted-1-azaanthraquinones bearing latent alkylating or H-bonding functionality
비마약성 진통제 DA-5018을 rat에 단희 및 반복 피하주사시 약물역학 및 조직 분포
비마약성 진통제 DA-5018의 투여경로에 따른 약물역학 및 조직 분포
Antiulcer effect of DA-9601, an extract of Artemisiae herba, and Its cytoprotective mechanism
Effect of DA-9601, an extract of Artemisiae herba, on alcohol-induced gastric damage
Nitric oxide mediates the gastroprotective action of DA-9601, an extract of Artemisiae herba, against ethanol and indomethacin
Favorable effect of DA-9601, an extract of Artemisiae herba, in animal models o f inflammatory Bowel Disease
Pharmacological study of newly synthesized prton pump (H+/K+ -ATPase) inhibitor, YJA20379-8
Acute intravenous and oral toxicity study of YJA20379 in rats
Preliminary toxicity study of YJA20379 by oral gavage administration to CD rats for 2 weeks
Inhibitory characteristics of a novel H+/K+ -ATPase inhibitor, YJA20379-8
Inhibitory properites of YJA20379s against urease of Helicobacter pylori
In vitro activity of novel pyrrolidinyl-thio carbapenem CW-270033 (I)
In vivo activity, stability to renal dehydropeptidase-Ⅰ (DHP-Ⅰ) and phamacokiiietics of novel pyrrolidinyl-thio caibapenem CW-270033 (Ⅱ)
The effect of dopamine lesion by 6-hydroxydopamine on mRNA expression of the muscarinic receptor subtypes (m1-m5) in rat brain
Monocrotaline으로 유발시킨 흰쥐 폐고혈압에 있어 enalapril과 gingko ext. 병용투여시 억제효과
Synthesis and antiinflammatory activity of phenoxy alkanoic acid derivatives(I)
Guinea pig 적출기도에 대한 β2 효능약인 clenbuter의 이완반응
Pharmacokinetics of a new reversible proton pump inhibitor, YH1885, after intravenous and oral administration of the drug to rats
Determination of a new antiulcer agent, YJA-20379-2, in human plasma and urine by high-performance liquid chromatography
Determination of a new antiulcer agent, YJA-20379-1, in human plasma and urine by high-performance liquid chromatography
Determination of a new antiulcer agent, YJA-20379-8, in human plasma and urine by high-performance liquid chromatography
Evaluation of hepatic, gastric, and intestinal first-pass effects of azosemide in rats
새로운 carbapenem계 항생제, DA-1131 을 dog에 정맥 투여시 약물역학, 조직분포, 및 담즙배설연구
새로운 carbapenem계 항생제, DA-1131의 mouse, rat, rabbit 및 dog에서 interspecies pharmacokinetics scaling 및 human prediction
Nucleotide-induced mucin release from primary hamster tracheal surface epithelial cells involves the P2u purinoceptor
ATP에 의한 기도 뮤신 유리 기전에 관한 연구
Clonidine patch제의 효능시험 : 혈압강하작용
Purification and characterization of rat intestinal maltase-glucoamylase
Blood glucose-lowering activity of mori folium water-soluble fraction
Bradykinin antagonistic activities of terfenadine
Differential sensitivity of basal and acetylcholine-stimulated nitric oxide activity on vaso-and neuronal responses
The anti-platelet aggregating effect of SK15051 in vivo and in vitro
The effects of evening primrose oil (EPO), vit.C and vit.E on nerve conduction velocity(NCV) in streptozotocin-diabetic rats
Ginsenoside Rg3의 혈소판 응집억제 효과와 그 기전에 대한 연구
20(S) 및 20(RS) from CKD602의 항암활성에 관한 연구
새로운 cephalosporin계 항생제 CKD 604의 animal scale-up에 관한 연구
Metabolism of the new insectcide flupyrazofos by rat liver microsomes
Determination of free fatty acids in human plasma after rapid derivatization by dabsyl cadaverine in HPLC
Simultaneous analysis of ibuprofen and acetaminophen in human plasma
Ion selective electrode에 대한 penicillinase의 최적 고정화 방법
Analysis of preservatives for quality control using capillary electrophoresis
Development of a HPLC method for the determination of protein modification with heterobifiinctional crosslinker containing pyridyl disulfide
Reversed-phase HPLC of radioiodinated salmon calcitonins
Degradation kinetics of somatostatin analogue octapeptide (RC160) in aqueous solution
Assay of flurbiprofen in rat plasma using HPLC with fluorescence detector
세파계 항생제 역가측정 및 평가(Ⅱ) - KST12027과 KST120278에 대하여 -
세파계 항생제 역가측정 및 평가 (Ⅰ) - KST120229와 KST120238에 대하여 -
대한약전 수재 의약품의 분석법 기기화에 관한 연구 - 프로게스테른 및 그 유도체의 HPLC 분석법 개발 -
Studies on the pattern recognition analysis of gas chromatographic organic acid profiles
Rapid screening for chiral acids by gas chromatographic retention index matching
Gas chromatographic profiling and screening of environmental water samples for organic acids
Identification and distinction of amide group and acid group in the drug using electrospray ionization mass spectrometry
마약 및 향정신성의약품 표준품제조에 관한 연구 (Ⅵ) - 페노바르비탈 및 치오펜탈 표준품 제조 -
Sphingolipids increase the antioxidant effect of α-tocopherol in heterogeneous system
RP-HPLC/ELSD를 이용한 인삼 사포닌의 미량 분석법
HPLC에 의한 알로에의 성분 정량
Analysis on Kojic acid and hydroquinone by GC and HPLC
Seperation and identification of multi-component in oxidative hair dye by GC and HPLC
Folic acid analysis in multivitamins by HPLC
Antihepatotoxic flavonol glycosides of Saururus chinensis against glactosamine induced cytotoxicity
Antihepatotoxic constituents of Saururus chinensis against carbon tetrachloride induced cytotoxicity
복분자 딸기 잎의 tannin에 관한 연구
한국산 주목의 세포배양의 의한 Taxane 유도체의 생산 (Ⅰ)
개비자나무 Cephalotaxus koreana Nakai의 성분
細辛의 地上部成分
Alkaloids from Aconitum chiisanense tuber
The constituents from the herb of Isodon excisus var. coreanus (I)
율무로부터 조직인자 저해제 분리
은행잎으로부터 항혈전작용 성분의 분리
채소의 조직인자 저해작용 검색
Antioxidant activity of some essential oils from aromatic plants
Antimicrobial activity of some essential oils from aromatic plants
백하수오의 화학성분
쿠마린 7-유도체의 초임계 이산화탄소 용해도 비교
부자의 강심성분인 higenamine 광학이성질체의 분리분석법
혈소판 활성화 인자 길항성분, pinusolide의 구조 활성 상관관계
Synthesis and PAF antagonist activity of α-substituted or α,β-disubstituted butyrolactone derivatives
곰팡이 분리주 SL. 60109가 생산하는 phosphoinositides(PI)-tumover 저해물질의 분리
Platelet anti-aggregation activity of high molecular aliphatic primary alcohols(I)
천연물로부터 멜라닌 색소생성 억제제 개발
Euphorbia 속 식물로부터 단리한 가수분해형 탄닌의 tyrosinase 활성 억제효과
생강나무의 소염, 진통작용에 관한 연구
가래나무로부터 세포독성물질의 분리 및 구조결정
Angelica keiskei (신선초)의 추출물, 분획물 및 화합물의 항돌연변이 효과
해조류 Pachymeniopsis elliptica의 메타놀 추출물이 고지방식이 흰쥐의 지질성분에 미치는 영향
Effects of Mbl lectins on cytokine gene expression from human peripheral blood mononuclear cells
민간약 「암초」의 생약학적 연구
Isolation and identification of anti-platelet activating factor compound from gentianae radix
천연물로부터 prolyl endopeptidase inhibitor의 탐색
Effects of Tussilago farfara on the anaphylaxis
Juglans sinensis 종자의 성분
20(S)-protopanaxadioI glucoside 외 방향선택적 역합성
새로운 항산화제 검색법에 의한 SOD mimic 천연 약물의 검색
민간약의 항산화능과 간보호효과 검토
Studies on pharmacological activities of Cichorium intybus
Evaluation of TPA-induced ornithine decarboxylase(ODC) inhibitors from plants for the detection of chemopreventive agents
[3H]PDBu binding assay to protein kinase C for the detection of chemopreventive agents in natural products
Evaluation of quinone reductase inducing activities for the development of chemoprevention agents from natural products
Evaluation of anti-hepatitis B viral activity from natural producrts
Screening of anti-inflanunatory agents from natural products
Bryostatin inhibits expression of differentiation markers induced by cell density in human keratinocytes, which is mediated by PKCα
Bryostatin inhibits expression of differentiation markers induced by cell density in human keratinocytes, which is mediated by PKCα
Licarin, potent inhibitor of ACAT, isolated from Machilus thunbergii
Polyacetylenes, potent inhibitors of ACAT, isolated from hairy root of Panax ginseng
Rhombicin, potent inhibitor of FPTase, isolated from Hedera rhombea
해양생리활성물질의 생명과학에서의 응용(3)-Gorgonian acabaria undulata에서 분리한 2차 대사물질들의 Na+,K+ -ATPase, cyclicAMP phosphodiesterase 그리고 혈소판 활성 억제작용-
해양생리활성물질의 생명과학에서의 응용(2)-Soft Alycyonium gracillimum과 gorgonian Muricella 속에서 분리한 2차 대사물질들의 Na+,K+ -ATPase, cyclicAMP phosphodiesterase 그리고 혈소판 활성 억제작용-
Jasmonic acid-induced capsidiol production in suspension culture of Capsicum annuum
Anti-hyperlipidemic effect of Arctium lappa
Effect of Cypems rotundus on lipidperoxidation, hepatotoxicity and analgesic activity
Sorbaria sorbifolia var. stellipila의 세포독성 성분
Inhibition of inducible nitric oxide synthase activity by polyacetylenes from Ginseng in LPS-activated macrphages
Sesquiterpene lactones from Saussurea lappa, inhibitors of NO production in LPS-activated macrohages
Herbal extracts with inhibitory effects on IL-3 bioassay
Inhibitory effects of herbal extracts on IL-5 bioassay, mIL-5-dependenl Y16 proliferation
Nucleotide sequence of a catechol 2,3,-dioxygenase gene from TOM plasmid of Pseudomonas cepacia G4
Nucleotide sequence of a catechol 2,3-dioxygenase gene and its promoter from chromosomal DNA of Achromobacter xylosoxidans KF701
Anti-angiogenic activity of novel derivatives of ursodeoxycholic acid (UDCA)
천연물로부터 Cyclooxygenase-2(COX-2) 저해제의 개발
Comparison of three specific activities of urinary dipeptidase
Purification of urinary dipeptidase and its comparison with two types of renal dipeptidases
Effects of exercise on gene expression of nitric oxide synthase and guanylate cyclase
Effects of age, dietary restriction and fish oil on free radical generation
같색거저리(Tenebrio molitor) larvae의 곤충의 생체방어반응인 encapsulation 관여하는 proteins의 정제 및 그 특성
같색거저리(Tenebrio molitor)의 유충으로부터 분리, 정제된 pro-phenoloxidase의 trypsin 및 SDS에 의한 활성화의 연구
항진균 활성을 가진 recombinant tenedn-3의 대량 분리, 정제 및 항진균력 규명
백편두(Dolichos lablab)로부터 elastase 및 serine protease inhibitor의 분리, 정제 및 그 특성에 관한 연구
한국산 참검정 풍뎅이 유충의 체액에 존재하는 prophenoloxidase activation system에 관여되는 componet의 분리 및 그 특성 조사
산화적 스트레스에 의한 apoptosis의 유발과 항산화효소, 항산화제 및 항암제와의 관계
The cytotoxicological effect of hydrogen peroxide on Drosophila Kc cell lines
Naphthoquinone 화합물의 백혈병 세포 U-937에 대한 분화 유도에 관한 연구
Effects of ceramide on cell cycle related proteins in HL-60 cells
Role of ceramide in regulation of cytosolic phospholipase A2 in U937 cell
Identification of substrates for protein methylase Ⅱ from porcine spleen
Chemical oversulfation and anticoagulant activity of acharan sulfate
YJA-20379 계열의 약물대사효소에 대한 영향
Identification of new bacteria species degrading glycosaminoglycans in human intestine
파고지로부터 프로스타글라딘의 생합성을 저해하는 물질의 분리 및 구조연구
Relationship between methylated arginines and NO synthase after partial hepatectomy
Radioprotective effect of a natural product preparation Y
Enhancement of mitogen-stimulated proliferation of low dose radiation-adapted mouse splenocytes
감염 B형 바이러스 유전자를 함유하는 재조합 종두바이러스의 제조
The anti-hepatitis B virus activities of derivatives of iridoid
트리아진류의 면역분석법 연구를 위한 항체 개발과 특성 조사
토양균 SNUS 9011-300에서 항생물질의 분리와 구조 규명
토양균 SNUS 9101-142에서 macrolactin A의 분리와 구조 규명
재조합 Klebsiella arogenes ureased의 분리 정제 및 urease 저해제에 대한 kinetic 연구에의 응용
재조합 Helicobacter pylori urease의 분리정제 및 Inhibitor 검색에의 응용
Effects of herbs on growth of Helicobacter pylori
Herpes simplex virus type 1으로부터 분리한 acyclovir내성균주의 동정
Inhibitory activity of tribactam against bacterial beta-lactamase
무우자갈버섯(Hebeloma crustuliniforme)등 담자균류의 면역활성에 관한 연구
무우자갈버섯(Hebeloma crustuliniforme)등 담자균류의 면역활성에 관한 연구
Bacillus subtilis의 acyl CoA synthetase 억제제 생산의 최적 조건 및 특성
Production of actinomycins by Streptomyces sp. V-8 and its mutant V-8-M-1
Resistant mechanism of Escherichia coli to various fluoroquinolones and the relationship between structure and activity
새로운 항진균 물질의 생물학적 활성 및 cytochrome P450 저해효과
Aflatoxin B1 suppressed NO production in murine peritoneal macrophages
Isolation and characterization of chitinase-producing Cytophaga sp. and purification of its chitinase
Purification and characterization of chitosanases from Aureobacterium sp.
유산균 및 생약의 rotavirus 감염 억제 효과
β-Glucuronidase 저해제 검색
장내세균에 의한 puerarin과 daidzin의 대사
Characterization of VP16 acidic domain in tetracycline repressor-VP16 fusion protein
Ampidllin/sulbactam에 내성을 갖는 대장균과 포도상구균에 대한 CH2150과 sulbactam의 항균효과 비교
β-Lactamase 생성균주에 대한 새로운 β-lactamase inhibiting compound와 β-lactam 항생제와의 병용시 향균효과
In vitro and in vivo β-lactamase inhibitory activity of 6-exomethylene penamsulfone derivatives
잣버섯 성분의 면역 세포 및 전사 인자 활성화 작용에 관한 연구
사람 말초혈액 단핵세포에 대한 영지 저분자분획의 영향
유박테리아에서의 macrolide계와 lincosamide계 항생물질에 의한 MLS 내성의 유도
Generation and characterization of MAbs against B cell tumor surface antigens
Characterization of HBsAg expressed in CHO cell
Glutathione Synthesis in the rat embryo and visceral yolk sac: differential regulation and response to embryotoxicants
Systemic immunosuppression in plasmacytoma bearing mice: I. Splenic lymphocyte proliferation
작약의 항고지혈 작용에 관한 연구
Caibamazepine의 임상약동학
Pharmacokinetics of aloesin in rats
Inhibitory effects of retinoids on development of squamous metaplasia from rat mammary epithelial cells and organoids cultured in matrigel
Dual effect of streptozotocin on the kainic acid-induced neurotoxic behavior in the rat
Localization of P-glycoprotein to brain microvascular endothelial cells or astrocytes
Phannacokinetics and blood-brain barrier permeability of epidermal growth factor
Inhibitory effects of isoquinoline alkaloids on catecholamine biosynthesis in PC12 cells
적출관류간 모델에서 저산소 및 산소재도입시 약물대사효소계 변동에 관한 연구
간장 허혈 및 재관류시 에너지 대사의 변동에 관한 연구
Changes in the glutamatergic nervous system following intracerebroventricular administration of AF64A in rats
Mapping cofilin-interactmg cytoplasmic domains o f (Na,K)ATPase
Increase of eosinophil chemotactic response to platelet-activating factor not but leukotriene B4 in allergic human subjects
Segmental antigen challenges decrease the optimal concentration of blood neutrophil chemotaxis to leukotriene B4 decrease in allergic subjects
Inhibititory activity of flavonoid methylates on the Histamine release from IgE-sensitized mast cells
Positive inotropic effect of water extract of Ganoderma lucidum on rat papillary muscle
The role of lipoxygenase in pain transmission
Capsaicin 유도체 및 내인성 물질의 통각신경세포에 대한 영향