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ㆍDrug Designs Based on Insect Defense Molecules
ㆍWhat is esndocr ine d is ru p to r and what are going on in JAPAN?
ㆍStudies on Antimetatic Activity of Antiplatelet Substance from Some Tropical Plants
ㆍSynthesis of Non-Classical Nucleosides as Potential Antiviral Agents
ㆍNew Targets for New Antibiotics
ㆍSubstrate Analogues of Aminoacyl-tRNA Synthetase Probe Active Site Residues and Inhibit Cell Growth.
ㆍ퀴놀론 항균제의 현황과 전망
ㆍEvaluation of A ntifungal Activities of 6-Arylamino-7 -halo -5,8 -quinolinediones
ㆍExtended Spectrum β-Lactamase 생성 그람옴성 간균
ㆍMacrolide-Lincosamide-Streptogramine B 계 항생물질의 내성 기전
ㆍ온도가역성 및 생체부착성 액상좌계의 개발
ㆍPreperation and Evaluation of Cyclosporin A Oral Controlled Release Dosage Form Using Solid-state Microemulsion
ㆍReceptor-mediated gene delivery to cells of hepatic origin by galactosylated macromolecule-peptide complex
ㆍThree Dimensional Structure Activity Relationships of Azaanthraquinone Derivatives as Potential Antitumor Agents
ㆍSolution Structure of an Antimicrobial Peptide Gaegurin 4
ㆍStructure based drug design by NMR
ㆍStructures of proteins which regulate actions of transcription factors
ㆍMbdes of Neuronal Injuiy Induced by Transient Focal Cerebral Isdienia in Rats
ㆍThe pathology of the respiratory system - lung cancer and asthma.
ㆍFATTY ACID OXIDATION DISORDERS AS METABOLIC CAUSES OF ASUDDEN DEATH
ㆍStudies on the Cell Cycle Modulators in Human Breast Cancer Cells
ㆍTotal Synthesis of Fluvirucin A1 as A Potent Antiviral Agent
ㆍStereoselective Synthesis o f β-amino-α-hydroxy acid and y-amino-β-hydroxy acid Using Palladium-catalyzed Oxazoline Fromation Reaction
ㆍDISCOVERY OF DW2282 FOR THE DEVELOPMENT OF NOVEL ANTICANCER AGENT
ㆍDesign and Synthesis of Chiral Ru(Ⅱ)L2 Complexes as Potential DNA Cleaving Agents
ㆍEndocrine Disrupting Issues in Human Health, and How We Can Protect it by Natural Products
ㆍRegulation of CYP2E1 and Tissue Protection Effect of CYP2E1 Inhibitor
ㆍQuantitative Low-Dose assessment of neurotoxin in the brain: Application of PBPK modeling
ㆍKiss-1, a novel metastasis-suppressor gene
ㆍAminophylline 복용시 물의 양어 theophyllineCTP)의 체내 동태에 미치는 영향
ㆍ모세담관막에는 TBuMA에 선택적인 ATP 의존성 배설 수송계가 존재한다.
ㆍCCI4 간장해가 유기 양이온의 담즘 배설에 미처는 영향 -간세포 Uptake 과정에 미처는 영향-
ㆍGC/MS룹 이용한 환쥐혈장에서의 DDB(diinethyl-4,4-diinethoxy-5,6,5,6-dimethylene dioxybiphenyl-2,2-dicarboxylate)의 정량분석범 개발과 rat을 이용한 pharmacokinetic study 에의 적용
ㆍCarrier mediated transport of YH-1885 across caco-2 cell monolayers
ㆍ엽산(folates)의 담좁 및 요중배설 기전에 관한 연구
ㆍ수술 후 장페색의 병태 상황에서 위장관 운동 기능을 측정할 수 있는 새로운 실험게의 개발
ㆍPreparation and Characterization of Poly(ethylene Glycol) Modified Salmon Calcitonins
ㆍStereoselective synthesis of 1β methylcarbapenem key Intermediate
ㆍOxazolidinone-cephalosporin quaternary ammonium salts
ㆍEffect of the aryl groups on the cytotoxicity and antitumor activity of 2-(1-oxyarylm ethyl)-1,4-dihydroxy-9,10-anthraquinones and 2-(1-oxyaryim ethyl)-1,4,9,10-anthradiquinones
ㆍNaphthazarin derivatives: synthesis, cytotoxic mechanism and evaluation o f antitumor activity
ㆍThe conjugate formation between glutathione and naphthoquinone derivatives and the relation to cytotoxic Activity
ㆍSynthesis of camptothecin analogues having Antitum or Activity: Modification of E ring or both E and A or B ring
ㆍSynthesis and Comparative Molecular Field Analysis (CoMFA) of Antitum or 3-Arylisoquinoline Derivatives
ㆍSyntheses of thiocarbamates, carboxamides, thioamides and cyclic thiocarbamates and their antiviral activities
ㆍAntithrombotic mechanisms of 2-chloro-3-[(4-acetophenyl)-amino]-1,4-naphathalendione: The effects on coagulation cascade and platelet activity
ㆍMenadione-induced vascular endothelial dysfunction and its possible Significance
ㆍ한국인의 장기조직 중 금속류의 분포와 표적장기에 관한 연구
ㆍProtective effect of NYK-1, NYK-2 on cisplatin induced nephrotoxicity
ㆍBenchmark Dose를 이용한 다이옥신의 비발암영향평가
ㆍ담체(carrier)Re-188-HEDP(HydroxyethyIidene diphosphate)의 표지와 생체 내분포에 미치는 영향
ㆍ서구의 약사 역할 확대와 한국의 약국의료보험과의 상관관계
ㆍAlteration of protease expression phenotype of mouse peritoneal mast cells by changing the microenvironment as demonstrated by in situ Hybridization histochemistry
ㆍEffect of ethanol on spontaneous phasic contraction in cat stomach
ㆍ암환자에서 반코마이신의 집단약몰동태학 모렐연구
ㆍInhibition of proliferation by wortmannin through the blokade of phosphatidylinositol 3-kinase in mast cell line P815
ㆍChanges of GABA receptor binding and GABA receptor subunit mRNA level in nitric oxide synthase inhibitor-infused rat brain
ㆍKosamol A, a novel prenylated flavonoid, arrests the cell cycle at G0/Gl stage
ㆍ새로운 염증성 대장염 치료제인 DA-6034의 acetic acid-유발성 대장염에서 치료효과
ㆍ수술 후 장폐색의 병태 상황에서 위장관 운동 기능을 측정할 수 있는 새로운 실험계 개발
ㆍPLC isozymes and MAPK mediated differential contraction in cat LES and esophageal circular muscle
ㆍMetabolism and excretion of fenfluramine in human urine
ㆍ기체크로마토그래피법을 이용한 혈중에서의 very long chain fatty acids (VLCFA)의 정량분석에 관한 연구
ㆍClassification of Ginseng radix using near infrared reflectance spectroscopy
ㆍQuantitative analysis of taurine using near infrared spectrometry (NIRS)
ㆍDetection of DNA bands on electrophoresis using indoine blue and methylorange
ㆍ양강 및 정향으로부터 C0X-2 저해제의 분리
ㆍCytotoxic novel polyacetylenes from the marine sponge Petrosia sp.
ㆍ진피(秦皮)의 Nitric oxide 생성 억제물질
ㆍArtemisia feddei의 Inducible Nitric oxide Synthase 억제물질
ㆍ오수유의 안지오텐신 Ⅱ 수용체 결합 저해활성
ㆍ백렴(Ampelopsis Radix)으로부터 분리된 전사활성 단백질 저해제, Momordins
ㆍMomordin I의 작용 기전 연구
ㆍ조구등으로부터 분리된 phospholipase Cy1 저해 활성 triterpene ester
ㆍDNA damage and cell death induced by salsolinol through oxidative stress
ㆍCloning and characterization of rat carbamoyl-phosphate synthetase in CHO cells
ㆍThe two open reading frames located just upstream of the human ADH5/FDH open reading frames are negative regulators of the ADH5/FDH gene expression
ㆍRegulation of cyclooxygenase via NF-kB by age and dietary restriction
ㆍHerpes simplex virus의 thymidine kinase를 발현하는 세포와 비발현 세포에서의 핵산유도체들의 세포독성
ㆍLarge-scale affinity-purification and characterization of human anti-P. aeruginosa Oprs antibodies as a therapeutic agent against P. aeruginosa infections
ㆍExpression, purification and characterization of Helicobacter pylori adhesin protein genetically linked to cholera toxin A2/B subunits in Escherichia coli
ㆍAntiherpetic activities of some flavonoids alone and in combinations with acyclovir and vidarabine
ㆍAntibacterial activity of antimycotic miconazole against methicillin-resistant Staphylococcus aureus
ㆍThe effect of rm IL-18 on the murine peritoneal macrophage
ㆍTumor-site dependent differential modulation of systemic immunity in RENCA bearing mice
ㆍGeneration of macrophages from early thymic progenitor cells
ㆍMethamphetamine이 면역반응에 미치는 영향
ㆍβ-Cyclodextrin 과 chitosan이 Flurbiprofen의 피부투과에 미치는 영향
ㆍGalβ1→4GlcNAc을 비환원 말단으로 하는 Asialofetuin 에 대한 β-galactosidase의 반응조건
ㆍ구내 염증치료용 구강점막 부착 패취제 개발
ㆍ피부상처 치료제 개발을 위 한 Leptospermum scoparium의 항균력 시험 및 제제화
ㆍYH1885의 결정 구조
ㆍ나프록센을 함유하는 페취의 제조 및 약물방출과 피부투과
ㆍEnalapril과 그 유도체들의 3차원 형태구조에 대한 분자동력학적 모델링 연구
ㆍCapsaicin 유도체 함유 외용제제의 안정성 및 경피흡수
ㆍMelatonin의 토끼 위 장관 흡수 연구
ㆍ형광분석법에 의한 poloxamer 407의 상전이 연구
ㆍIdentification of major metabolite of new platinum (Ⅱ) complexes, KHPC-002 and KHPC-006 in Rats.
ㆍOptimization study on the formulation of roxithromycin dispersible tablet using experimental design
ㆍAir atomization을 이용한 bifidobacteria 함유 microparticles의 제조 및 내산성 연구
ㆍ고분자 코팅막 조성 번화에 따른 melatonin의 막투과성 고찰
ㆍTacrine의 혈중 뇌중 동태에 관한 연구
ㆍ정상 및 hepatoma rat에서의 lipiodol emulsion에 함유된 adriamycin외 간조직분포: Microdialysis 법을 이용한 연구
ㆍ실험적 뇌수막염에서 benzyl penicillin의 뇌척수액 클리어런스의 감소: Nitric oxide synthase의 관련성에 관한 연구
ㆍ담도결찰 흰쥐에서 마디풀(Polygonum aviculare L.)의 간섬유화 억제효과
ㆍProcollagen N-terminal peptide 확인을 위한 표준물질 및 항체생산에 관한 연구
ㆍβ-carotene 함유 alginate beads의 용출에 미치는 계면활성제의 영향
ㆍCerfradine을 함유한 alginate bead의 용출 특성
ㆍFelodipine microsphares의 생체 이용율에 관한 연구
ㆍSelf-emulsifying system 을 이용한 난용성 약물의 drug delivery (Ⅳ) indomethacin 의 selfemulsifying drug delivery system
ㆍPoly(ortho esters)를 이용한 Nifedipine의 반고형 이식제제의 제조 및 평가에 관한 연구
ㆍ반고형 외용제제에서의 PGE1의 안정화 및 투과촉진에 관한 연구
ㆍ단백분해성 펜타펩타이드인 Pz-peptide의 간내 이행 기전
ㆍ방사성 활액막 절제술용 Re-188 주석 교질의 제조
ㆍDevelopment and optimization of TTS containing clebopride
ㆍImprovement of dissolution rate of poorly water soluble drug using self-microemulsifying drug delivery system
ㆍDehydroevodiamine(DHED)의 혈구분배 및 혈장단백결합률
ㆍDehydroevodiamine(DHED)의 혈장, 담즙 및 요중 정량법
ㆍDehydroevodiamine(DHED)의 생체내 동태
ㆍPharmacokinetic and pharmacodynamic evaluation of cyclosporine a as O/W-emulsion formulation
ㆍRegulated albumin release from biodegradable hydrogels composed of glycidyl methacrylate dextran and poly(ethylene glycol) macromer
ㆍReversal of multidrug resistance by p-glycoprotein inhibitors in oral administration of paclitaxel
ㆍThe effect of various penetration enhancers on the percutaneous absorption of prostaglandin E1
ㆍ난용성의약품의 초미분체 조제와 그 약제학적 유용성의 평가
ㆍA study on the effect of HPE-101 on human eythrocyte membrane
ㆍ리포솜 봉입이 Rhodamine 123의 Caco-2 세포 단층 투과성에 미치는 영향
ㆍ약물의 담즙배설을 예측할 수 있는 샌드위치형 간세포 배양계의 개발
ㆍPrepration and characterization of tablets containing cefatrizine propylene glycol enteric-microencapsulated or microagglomerated by spray-drying method
ㆍThe effect of skin permeation enhancers on the transdermal delivery of testosterone from a novel soft hydrogel
ㆍEffect of pore formers on the controlled release of antibiotics from a polymeric device
ㆍSynthesis and characterization of immunotoxins containing deglycosylated ricin A-chain
ㆍA new route to the synthesis of cephem derivatives
ㆍOptical resolution of [3.2.0] bicyclic amines with L-tartaric acid
ㆍSynthesis and antimicrobial activity of new cephalosporin having a heterocyclic-pyrrolidinylthio moiety at the C-3 position
ㆍSynthesis of 3-substituted-7-halocephems as β-latamase inhibitors
ㆍMethionine analogues as inhibitors of methionyl-tRNA synthetase as potential antibacterial Agents
ㆍSynthesis of L-sangivamycin and toyocamycin analogues, and their inhibitory activities of Ser/Thr protein kinases
ㆍProtein kinase C ligands based on templated derived from 5,5-acyloxyhydroxymethyl tetrahydrofuran
ㆍSynthesis of new monoterpenenoid as potential antitumor agents
ㆍ2-(1-oxyiminoalkyl)-1,4-dihydroxyanthracene-9,10-diones: Synthesis and evaluation of antitumor Activity
ㆍSynthetic approaches of natural benzo[c]phenanthridine alkaloids
ㆍAn efficient synthesis of benzo[c]phenanthridine skeleton
ㆍ새로운 modified nucleosides의 합성
ㆍ2-알킬아미노퀴놀린계 유도체의 분자설계, 합성 및 세포득성
ㆍ1-azaanthraquinone-3-carboxamide 유도체의 합성 및 세포독성
ㆍA novel class of platinum complex(KHPC-014) exhibiting selective cytotoxicity to various cancer cell-lines and normal kidney cells
ㆍSelective cytotoxicities of novel platinum(Ⅱ) complex {[Pt(Ⅱ)(cis-DACH)(DCE)]2NO3} on human ovary cancer cell-lines and normal kidney cells
ㆍ메실산 가백세이트 유도체로부터 항전이효과
ㆍSynthesis and evaluation of antifungal activities of 6-(substituted-phenylamino)-7-chloro-5,8-quinazolinediones
ㆍCyclooxygenase-2 저해제의 합성과 그 생물학적 활성
ㆍ새로운 σ -opoid 유도체들의 합성에 관한 연구
ㆍDesign and synthesis of cyclic peptide ligands for the recently discovered melanotropin receptor subtypes
ㆍ항염효과가 기대되는 4-oxo 1,2-benzothiazine 유도체의 합성
ㆍThe syntheses and biological evaluations of 5-pyrrolocarbonyl-2-(pyridylmethylsulfinyl)benzimidazole derivatives as gastric antisecretory agent
ㆍPreparation of 5-pyrrolyl-6-halo-2-(pyridylmethyl-sulfinyl)benziinidazole derivatives as antiulcer agents
ㆍSynthesis and aldose reductase inhibitory and antioxidant activity of new chalcone derivatives
ㆍ2,5-Dihydro-4-methyl-2-phenyl-1,5-pyrido(2,3-c)thiazepine-3-carboxylic acid ester의 합성
ㆍEnalapril과 그 유도체들의 3차원 형태구조에 대한 분자동력학적 모델링 연구
ㆍ새로운 kojic acid 유도체의 합성과 tyrosinase 저해효과
ㆍStructural discrimination between the N-substituted 2-methoxycarbonyl-9-azabicylo [4.2.1]-and [3.3.1]nonane isomers
ㆍTotal synthesis of (± )-homoepibatidine analogues
ㆍStereoselective synthesis of (±)-epibatidine analogues: (±)-2β-(2-chloro-5-pyridinyl)-8-azabicyclo[3,2,1]octane
ㆍSynthesis of torilin derivatives
ㆍLewis acid promoted intramolecular cyclization of between acetal and acetylene in acyclic system
ㆍNew synthetic method for the synthesis of 4,5-disubstituted-pyrrolidinone by palladium catalyzed dicarbonylation from amino acid
ㆍAsymmetric Michael reaction using C2 symmetric chiral malonamide
ㆍSynthesis of optically active 7 y-azetidinyl-β-hydroxy-α-amino acid moiety of mugineic acid
ㆍA new method for direct conversion of allyl ethers into allyl carbamates using chlorosulfonyl Isocyanate
ㆍSolid phase synthesis of Aza-peptidomimetric Library using a Fmoc-Hydrazine Scaffold
ㆍOptimal synthesis conditions of hydrotalcite
ㆍDesign and synthesis of chiral cycloruthenated complexes and their properties
ㆍUrinary excretion of dextromethorphan in human
ㆍTeratogenicity of heavy metals, assayed by the rat embryonic midbrain cells
ㆍInhibitory effect of nitric oxide on the cyplal gene expression
ㆍThe effect of hypoxic condition on the regulation of CYP4501A1
ㆍNitric oxide and hypoxia effect on TCDD induced EROD activity
ㆍEffect of biphenyl dimethyl dicarboxylate (DDB) on drug metabolizing enzyme, CYP450 in rat liver
ㆍ천연물질 KC-1 의 cisplatin 유도 신장독성에 대한 억제효과
ㆍ소변중 대마성분 확인에 사용되는 예비실험법의 비교
ㆍ흰쥐에 amitriptyline 경구투여시 시간경과에 따른 amitriptyline파 그 대사체의 혈중농도번화 및 amitriptyline파 관련된 사망사례
ㆍMetabolism of S-containing amino acid in mice fed betaine for 2 weeks
ㆍA novel membrane-associated 48 kDa phospholipase A2 in leaves of higher plant Vicia faba is activated by calmodulin and inhibited by dephosphorylation
ㆍActivation of neutral and Mg2+-dependent sphingomyelinase is involved in glutamate-induced neocortical neuronal cell death
ㆍOxidized low density lipoproteins (oxLDL) induce activation of cytosolic 100 kDa phospholipase A2 leading to murine macrophage RAW 264.7 cell death
ㆍDetection of cytosolic 100 kDa phospholipase A2 activity in cytosol of bovine brain
ㆍA brain form of Ca+ -independent phospholipase A2 (iPLAa) is different from the 80 kDa non-brain form of iPLA2
ㆍDepletion of glutathione activated a novel 75 kDa form of neutral, cytosolic, Mg2+ -independent sphingomyelinase leading to murine dopaminergic neuronal cell death
ㆍEffects of zinc chloride on the immunobiological responses of lipopolysaccharide
ㆍEnhancement of menadione-induced cytotoxicity to platelets by the presence of blood plasma
ㆍFumonisin-induced activation of Caspase 3 is related to the disrupted sphingolipid metabolism in LLC-PK1 cells
ㆍThe antidiabetic and detoxifying activities of yeast-vanadate complex
ㆍNovel ginseng saponin metabolites
ㆍStudies on safety evaluation of imported cosmetics -Investigation on skin irritancy of cosmetics by human patch testing-
ㆍ면역세포를 carbofuran에 직접 노출시 그 반응성에 미치는 영향
ㆍCarbofuran의 장기투여가 C57BL/6 웅성 생쥐의 면역능에 미치는 영향
ㆍMB-18의 항혈소판 작용
ㆍAntiplatelet aggregation mechanisms of green tea catechins and (-)-epigallocatechin gallate
ㆍAntipiatelet aggregation mechanism of 2-chloro-3-[4-(ethylcarboxy)-phenyl]-amino-1,4-naphthalendione
ㆍUVA, UVB 조사에 의 한 광예민성화합물의 RBC-hemolysis, Yeast test 및 MTT assy 비교연구
ㆍEffects of geldanamycin on prostaglandin production in rat-2 cells
ㆍEffect of herbal medicine on overiectomized rat
ㆍEffects of Paljin-tang on the liver of arsenic-poisoned rats
ㆍEffect of antioxidants on the in vitro formation of 8-hydroxy-2`-deoxyguanosine by oxidative stress
ㆍEffect of subacute lead exposure on the cerebellar glial cells
ㆍChanges in the serotonergic nervous system following intracerebroventricular administration of AF64A in Rats
ㆍAdvantages of calcium green-1 over other fluoresecent dyes in measuring cytosolic calcium in Platelets
ㆍ한국인의 장기조직 중 금속류의 분포화 표적장기에 관한 연구
ㆍ수종 생약의 murine embryonic hepatocyte BNL-cl.2 cells 보호 효과
ㆍThe influence of melatonin on the humoral and non-specific immune response of cadmium
ㆍNeutrophil이 생성하는 reactive oxygen radical의 생성억제 및 제거활성을 가지는 천연물 검색
ㆍInhibition of reactive oxygen species-induced genotoxicity by alpinia officinarum and its major flavonoid, Galangin
ㆍThe effects of nalbuphine on the spontaneous locomotor activity and primary humoral immune response in mice.
ㆍAlterations in the levels of glutathione, taurine, and various amino acids in liver and plasma of mice treated with betaine
ㆍInhibition of platelet aggregation and phosphoinositides breakdown by 2-chloro-3-[4-(ethylcarboxy)-phenyl]-amino-l,4-naphthalendione in human platelets
ㆍ천연물질 KC-1, NYK-1, NYK-2의 Cisplatin 유도 신장독성에 대한 억제효과
ㆍChemically-induced platelet lysis causes vasoconstriction by release of serotonin
ㆍThe effect of Salicornia herbacea L. on the CCl4-Induced hepatotoxicity in rats
ㆍ용접흄 발생 장처를 이용한 stainless steel arc 용접흄의 급성적 노출 유해성조사
ㆍVanadium파 yeast cell의 결합체 형성과 항당뇨 효과
ㆍComplestatin antagonizes the kainate-induced neurotoxicity in cultured chick telencephalic neurons
ㆍNMDA receptor antagonists enhance 5-HT2 receptor-mediated behaviors, head-twitch responses, in reserpine pretreated mice
ㆍAcute oral and intravenous toxicity of YJA20379-8 to the rat
ㆍAcute oral and intravenous toxicity of YJA20379-2 to the rat
ㆍBiochemical and pharmacological characteristics of a newly synthesized proton pump (H/K+-ATPase) inhibitor, YJA20379-3
ㆍEffects of chlorhexidine on structural parameters of total lipid liposomes extracted from Anaerobic Bacterial Membranes
ㆍPharmacokinetics of losartan and its metabolite, exp3174, after intravenous and oral administration of losartan to rats with streptozotocin-induced diabetes mellitus
ㆍOnion has more beneficial antithrombotic effect in diabetic rat
ㆍ3T3-L1 Cell에서 상엽 물 및 에탄올 추출물이 glucose transporter, ACC, FAS gene expression에 미치는 영향
ㆍStreptozotocin 유발 세포독성에 대한 상엽의 보호활성
ㆍ고탄수화물식이 섭취 마우스에서 acarbose의 glycosidase, glucose transporter 및 leptin 유전자 발현에 미치는 영향
ㆍPhagocytic activity of ethyl alcohol fraction of deer antler in murine peritoneal macrophage
ㆍA suppressive component on phagocytic activity of peritoneal macrophage in Aurantii immaturi pericarpium
ㆍPhagocytic activity of lithospermi radix on peritoneal macrophage in mice
ㆍ흰쥐에서 selegiline 및 Ginkgo biloba extract(EGb 761)외 병용처치시 중추신경계에서의 상호작용
ㆍBradykinin에 의한 혈관반응에 있어 Enalapril 과 Ginkgo biloba extract(EGb 761)의 영향
ㆍCytotoxicity and effect on cell cycle of norcepharadion B to cancer cells in vitro
ㆍ새로운 PDE저해제 CJ-1082의 항 천식 약효
ㆍIn vitro metabolism and inhibition study of DDB with native human liver microsomes
ㆍHematological changes in the hypertensive rats induced by lead intoxication
ㆍComparative neuroprotective activities of KC-508 and KC-497, glycine site antagonists with MK-801 in a rat model of permanent focal ischemia
ㆍ저농도의 arachidonic acid를 처리한 혈소판 cyclooxygenase-1(COX-1) 평가모델에서 NSAID외 저해 활성 변화
ㆍ우루소데옥시콜린산이 허혈성 심장 기능에 미치는 영향
ㆍTetrandrine이 lipocyte의 activation에 미치는 영향
ㆍEffect of renal denervation and glibenclamide on renal action of SKP-450, K+ channel Opener, in Dog
ㆍRenal action of BRL 34915, K+ channel opener, in dog
ㆍRenal action of idazoxan, α2-adrenergic blocker, in dog
ㆍEffect of elimination rates on drug distribution in the hydrodynamic analogue of biexponential decay Model
ㆍCetirizine 유도체의 합성 및 항히스타민, 항브라디키닌 효과에 관한 연구
ㆍPurinergic mechanism on electrical field stimulation-mediated vasorelaxation in rat aorta
ㆍ맥문동 수추출액이 CC14로 유도된 흰쥐 간독성에 미치는 영향
ㆍSignal transduction mechanism via adenosine receptor in feline detrusor muscle
ㆍThe mechanism on acetylcholine-induced contraction in cat detrusor muscle
ㆍInhibition of the famesylation of recombinant human K-ras4B by YH3096
ㆍDisruption of the post-translational processing of oncogenic K-ras by YH3096
ㆍ팔선 양조용수외 세포독성 및 항암활성
ㆍEffects of polycyclic hydrocarbons on human cytochrome P4501A2 gene (CYP1A2) promoter Activity
ㆍThe effect of chronic electroconvulsive shock on the expression of phospholipase C in rat brain ： Immunohistochemical study
ㆍProduction and characterization of monoclonal antibody against Mud protein; its application for determination of the effect of retinoic acid-deficiency on the expression of Mucl protein from hamster tracheal surface epithelial (HTSE) cells
ㆍ두릅나무 근피의 항염증작용
ㆍ해조류의 고혈당 조절작용
ㆍ다시마의 체중증가 억제작용
ㆍEffects of Propolis on Wound healing in Rats
ㆍIFNy and IL-4 targeted gene therapy for the atopic allergic diseases
ㆍAnti-allergic action of resveratrol and related hydroxystilbenes
ㆍActivation of Fe £ RI inhibits the pyruvate kinase activity by directly interacting through y chain
ㆍAnti-allergic action of tanshinone and related derivatives
ㆍStudies of signal transduction pathway of the high affinity IgE receptor (Fc£RI) using yeast two-hybrid system
ㆍInhibition by Liocolae vermiculus of adjuvant-induced angiogenesis in the mouse pouch
ㆍMultidrug-resistance reversal activities of verapamil, quinidine, cyclosporin A, nicardipine and tamoxifen
ㆍExpression and functional analysis of tissue inhibitor of metalloproteinasel (TIMP1) wild-type and mutants expressed by baculovirus/insect cell system
ㆍComparison of metabolites in rat urine between L-deprenyl and methamphetamine administration by capillary electrophoresis
ㆍL-deprenyl (selegiline) prevents the 6-hydroxydopamine-induced depletion of dopamine in Rat Brain
ㆍNitric oxide synthase외 만성억제로 유발된 고혈압에서 혈관조직내 adrenaline성 수용체와 angiotensin II 수용체 반응의 변화
ㆍGas chromatographic profiling and screening of water samples for phenols
ㆍSeparation of hydroxylated and methoxylated flavonoids by micellar electrokinetic capillary chromatography
ㆍSimultaneous gas chromatography of organic acids and amino acids in Baekgangjam and Dongchunghacho
ㆍGas chromatographic profiling analysis of urinary polyamines as N-ethyloxycarbonyl derivatives
ㆍImpurity profiling analysis of illicit methamphetamine by gas chromatography
ㆍAnalysis of chlorpromazine in postmortem specimens by GC and GC/MS
ㆍGC/MS를 이용한 뇨외 유기인계 화합물의 대사물에 관한 연구
ㆍStructural studies of biomolecules by tandem analysis of capillary electrophoresis and MALDI-TOF MS
ㆍDetermination of paeonol and paeoniflorin in moutan root-bark by capillary electrophoresis(CE)
ㆍ의약품의 품질평가에 관한 연구 (I) -CE를 이용한 효소제의약품의 품질연구(염화리소짐 제제) -
ㆍ대한약전시험법에 관한 연구 - 린코마이신의 기기분석에 관하여 -
ㆍStudies on assay, content uniformity and dissolution of domperidone tablets
ㆍ성분검출에 의한 오수유의 확인
ㆍp-Quinone 유도체에 의한 Enoxacin의 정량
ㆍA New Sesquiterpene from Tussilago farfara
ㆍStructure identification of a new proton pump inhibitor, IY-81149
ㆍDevelopment and validation of HPLC for the analysis of IY-81149
ㆍDetection of DNA on gel electrophoresis using Crystal violet and Methyl orange
ㆍStaining of protein bands in polyacrylamide gels using Coomassie brilliant blue R and Phenosafranin
ㆍMeasurement of protein concentration using an Eosin Y dye
ㆍA simple and sensitive staining of proteins separated on SDS-PAGE with Zincon-methyl v iolet.
ㆍ크라이신의 살리실 유도체에 관한 분석학적 연구
ㆍ크라이신 7-O-톨루익산의 물성 및 활성검색
ㆍ국산 propolis에서의 tectochrysin의 확인 및 정량
ㆍ7-O-p-Fluorobenzoylchrysin의 물성 및 혈당강하효과
ㆍAnalysis of sugar alcohols in amino acid infusion by Bio-LC
ㆍDetermination of cisapride in rat serum samples using microbore HPLC with column-switching
ㆍMetabolism of myristicin in rat isolated perfused liver
ㆍSeparation of stereoisomers and diastereomers of CFC-222, a new fluoroquinolone by HPLC methods
ㆍDetermination of terbutaline enantiomers in human plasma by achiral-chiral high performance liquid chromatography
ㆍChiral derivatization of β -blockers with (-)-menthyl chloroformate
ㆍ화장품의 특수성분에 관한 연구(X) -Ion chromatography에 의한 화장품중의 유기산 분석법 -
ㆍNew sensitive analysis of lovastatin acid by HPLC with UV detection in human volunteers
ㆍNaphthalene-2,3-dialdehyde as precolumn labeling reagent for sphingoid bases by reversed-phase liquid chromatography with fluorescent detection
ㆍIdentification of IY81149 and its metabolites in the rat plasma using the on-line HPLC/ESI mass spectrometry
ㆍCharacterization of immunotoxins by capillary electrophoresis and MALDI-TOF mass spectrometry
ㆍMALDI-TOF mass spectromery for characterization of mono-PEGylated salmon calcitonin
ㆍHPLC-ECD를 이용한 흰쥐뇌의 부위별 Y-aminobutyric acid 및 glutamic acid의 분석
ㆍ할미질빵(Clematis trichotma) 줄기 성분
ㆍAntioxidative effect of Rheum undulatum
ㆍ노인성 치매 관련 생약의 항산화 효과
ㆍ보라우무(Symphyocladia latiuscula)의 항산화 활성과 그 활성 성분의 분리 및 동정
ㆍInhibitory effects of some plants extracts on HIV-1 and its essential enzymes
ㆍ사방오리나무외 항 HIV-1 활성화합물
ㆍ권삼(Polygonum bistorta)의 활성성분 연구
ㆍEffects of signal transducers on production of baccatin Ⅲ in taxus cell culture
ㆍ오미자로부터 분리된 lignan 화합물의 PAF 길항효과
ㆍ해동피에서 분리한 사포닌의 세포독성, 항돌연변이 및 항산화 효과
ㆍTwo new isoflavone glycosides from the flower of Pueraria thunbergiana
ㆍAntiangiogenic and antiinvasive antivities of Torilin isolated from Torilis japonica and polyoxypregnane glycosides isolated from Cynanchum wilfodii
ㆍ담자균류로부터 prolyl endopeptidase 및 acetylcholine esterase inhibitor의 탐색
ㆍAlkaloids from the roots of Cynanchum caudatum and their structure-antioxidative activity Relationships
ㆍ知母로부터 새로운 norlignan 화합물의 분리 및 hyaluronidase 억제효과
ㆍInhibitory effect of abietane diterpenes isolated from Salvia miltiorrhiza on hepatitis B Virus Reverse Transcriptase
ㆍ대파중의 벼생장 촉진물질
ㆍMonoamine oxidase inhibitors from Basidiomycete sp. 8082
ㆍ산앵도나무 잎 성분이 aldose 환원효소에 미치는 효과
ㆍ산앵도나무(Vaccinium Koreanum)잎 성분의 분리 및 화학구조
ㆍAntioxidation activity of Acanthopanax divaricatus var. albeofructus
ㆍAntioxidant effect of astragalic radix
ㆍLignan components from the flower buds of Magnolia fargesii
ㆍ까치버섯(Polyozellus Multiplex)으로부터 prolyl endopeptidase inhibitor의 분리
ㆍChitin synthase Ⅱ inhibition of gomisin N and wuweizisu C from Schizandra chinensis
ㆍChitin synthase Ⅱ inhibitory activity of ursolic acid, isolated from Crataegus pinnatifida
ㆍAsitrimin, annonacin A, cytotoxic annonaceous acetogenins from the seeds of Asimina triloba
ㆍInhibition of nitric oxide production by polyacetylenes from Angelica gigas in LPS-activated RAW 264.7 cells
ㆍAnnocherin A, B, C and corossolin, three novel and a known cytotoxic annonaceous acetogenins from the seeds o f Annona cherimolia.
ㆍ太子蔘의 생리활성
ㆍ차전자의 활성성분 연구
ㆍA triterpene glycoside from leaves of Acanthopanax divaricatus var. albeofructus
ㆍ나도냉이 (Barbarea orthocerus LED)의 tyrosinase 저해활성 물질
ㆍProduction of antibody against 20(S)-protopanaxatiol and triol group saponins of Panax ginseng C.A.Meyer
ㆍStudies on the production of essential oils by plant tissue culture of Shizonepeta tenuifolia Briq. var. japonica Kitagwa
ㆍCytotoxic triterpenes from Physocarpus internedius
ㆍInhibitory effect of abietane diterpenes isolated from Salvia miltiorrhiza on hepatitis B virus reverse transcriptase
ㆍ손바닥선인장의 효소저해작용 및 항산화작용 연구
ㆍ참취로부터 수용성 알카로이드 분리
ㆍ참취로부터 조직인자저해제 분리
ㆍ채소류외 dopamine β-hydroxylase 및 monoamine oxidase 저해작용 검색
ㆍPhenolic compounds from the leaves of Clerodendron trichotomum
ㆍBenzylalcoholglycoside from Gastrodia elata
ㆍConstituents and quantitative analysis from the leaves of Acanthopanax divaricatus f. nambunensis
ㆍPhenylpropanoids from the aerial parts of Rumex gmelini (I)
ㆍFlavonoids from the leaves of Caragana chamlagu
ㆍ수종 생약의 murine embryonic hepatocyte BNL-cl.2 cells 보호 효과
ㆍIsolation of phospholipase C inhibitors from Erythrina senegalensis (Leguminosae)
ㆍ팔선 양조용수의 세포독성 및 항암활성
ㆍActivators and inhibitors of thrombin from mushrooms
ㆍInhibitors of extracellular protease of Acanthamoeba castellanii from mushrooms
ㆍEffect of Asterina pectinifera lectins of tumor cells and cytokine production in human PBMC
ㆍLCC 렉틴의 면역기능 조정효과 ： 사람 말초혈액 단핵세포에서 사이토카인 생성양상
ㆍLignans from Sorbaria sorbifolia var. stellipila
ㆍInhibition of topoisomerase-mediated DNA cleavage by Lycoperdon perlatum
ㆍ감초의 β-glucuronidase 저해작용과 간장보호효과
ㆍ빈랑의 α-glucosidase 저해효과
ㆍMefenamic acid 유도체 합성과 생물활성
ㆍ사철쑥과 그늘쑥의 다당체 분획 연구
ㆍA cyclitol derivative as a topoisomerase I inhibitor from a marine sponge Petrosia sp
ㆍ백지로부터 항염작용이 있는 물질의 분리
ㆍCercis chinensis의 잎으로부터 단리한 phenol성 화합물 및 tyrosinase 활성 억제효과
ㆍ조개나물 전초의 화학성분(Ⅱ)
ㆍ민간약「노루귀」생약학적 연구
ㆍ수종 생약의 murine embryonic hepatocyte BNL-cl.2 cells 보호 효과
ㆍCytotoxic constituents of Gymnaster koraiensis
ㆍ손바닥선인장의 열메와 줄기의 생리활성 연구(1)
ㆍRegulation of pulmonary reactive oxygen species generation by age and dietary restriction
ㆍ1d와 유사한 새로운 HLH유전자의 클로닝 및 특성연구
ㆍTetR-mediated transcriptional activation system in animal virus
ㆍDefferential expression of ATX according to the metastatic potentials of tumor cells
ㆍ知母로부터 새로운 norlignan 화합물의 분리 및 hyaluronidase 억제효과
ㆍPurification of protein methylase Ⅱ in Helicobacter pylori
ㆍAn endogenous proleinacious inhibitor for S-adenosyl-L-methionine-dependent transmethylation reactions ; Identification of ACP (acyl-carrier protein) like glycoprotein
ㆍIdentification of nitric oxide Synthase in Staphylococcus epidermidis
ㆍPurification of NO synthase in Staphylococcus aureus
ㆍThe role of p70s6k signaling pathway on the growth of the cancer cell
ㆍCeramide-mediated apoptosis involves modulation of p27kip1 expression and cyclindependent kinase activities
ㆍEffect of glutathione on anticancer agents-induced apoptosis
ㆍCopper-mediated enhancement of salsolinol-induced DNA strand scission and genotoxicity
ㆍPhysiological concentrations of Pi have an inhibitory effect on the phosphotyrosyl phosphatase activity of plasma alkaline phosphatase
ㆍ들깨잎 polyphenol oxidase의 세포내 분포 및 특성
ㆍ은행잎 polyphenol oxidase의 세포내 분포 및 효소반응 생성물의 특성
ㆍ수종 생약이 Hepatoma cell line의 증식에 미치는 영향
ㆍThe preparation and structure of tetraarsenic hexaoxide
ㆍToxicity of tetraarsenic hexoxide
ㆍNucleotide sequence of 2-hydroxymconic semialdehyde dehydrogenase gene from Pseudomonas cepacia G4
ㆍNucleotide sequence of acetaldehyde dehydrogenase gene from Achromobacter xylosoxidans KF701
ㆍCharacterization of the pcbD gene encoding 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase from Pseudomonas sp. P20
ㆍInhibitory effects of herbal extracts on tumor necrosis factor
ㆍInhibitory effects of anti-asthmatic agents on proinflammatory cytokines
ㆍAnti-inflammatory effects of α-viniferin and epiafzelechin
ㆍ1-(2-furyl)-3-(sub.(R)-phenyI)propenone 유도체들의 정량적 구조-활성 상관관계 (QSAR)
ㆍUse of recombinant human cytochrome P450 1A2 expressed in Escherichia coli for bacterial mutagenicity assay
ㆍInhibition of cyclooxygenase/lipoxygenase from human platelets by polyhydroxylated/methoxylated flavonoids isolated from the several medicinal plants
ㆍAntiarthritic and analgesic activity of ginkgetin, a plant biflavone from Ginkgo biloba leaves
ㆍEffects of naturally-occurring flavonoids on nitric oxide production in the macrophage cell line RAW 264.7 and their structural-activity relationships
ㆍCu2+-catalyzed oxidative degradation of Thyroglobulin
ㆍPLA2-mediated release of GPI-anchored Zn2+-glycerophosphocholine cholinephosphodiesterase from ox brain membrane
ㆍInhibition of mouse skin tumor promotion and phorbol ester induced NF-kB activation in cultured HL-60 cells by diarylheptanoids structurally related to curcumin
ㆍInhibition of proliferation by wortmannin through the blokade of phosphatidylinositol 3-kinase in mast cell line P815
ㆍRegulation of NF-kB activation by age and dietary restriction in brain
ㆍDefferential expression of ATX according to the metastatic potentials of tumor cells
ㆍInduction of apoptosis and endogenous changes of sphingolipid metabolites by FTY-720 treatment in LLC-PK1 cells
ㆍAntiviral activities of various water and methanol soluble substances isolated from Ganoderma lucidum
ㆍUp-regulation of protein kinase C iso forms protects RAW264.7 macrophages from nitric oxide-induced apoptosis
ㆍThe characterization and immune response of microglia on Friend virus infection
ㆍHeterologous expression, purification and biochemical characterization of chl D gene involved in 2-deoxy-D-rhamnose biosynthesis from Streptomyces antibioticus Tu 99
ㆍInhibitory effect of immediate hypersensitivity by Perilla frutecens
ㆍDevelopment of a reporter gene using arylsulfate sulfotransferase (ASST)
ㆍ옥사졸리디논계 신규 화합물 CJ-10853의 항균 약효
ㆍ한국형 유산균의 완하 및 항사하 효과
ㆍ돼지 비장에서 phospholipase A2의 분리 정제 및 억제제 개발
ㆍBacillus sp. 960904가 생산하는 lipoxygenase 억제제 분리 및 구조 분석
ㆍPhenazine류 및 butanol 주출성 acyl-coA 합성효소 억제 물질의 분리 및 구조 분석
ㆍ다양한 그람음성균에 작용하는 lipopolysaccaride-outer membrane protein microsome vaccine외 독성 및 유효성 확인
ㆍ폐염 구균 dnaK operon의 클로닝 및 전사조절에 대한 연구
ㆍTherapeutic efficacy of human anti-P. aeruginosa oprs antibodies against P. aeruginosa infection in mice
ㆍ비소가 마우스의 골수세포 분화에 미치는 영향에 과한 연구
ㆍPurification and gene cloning of a chitinase from Cytophaga sp. HJ
ㆍ천연물로부터 알코올 탈수소효소, 알데하이드 탈수소효소 활성 저해제 선별
ㆍDemonstration of cytotoxic T cell response to HBV antigen in putative nonresponder mice.
ㆍCharacterization of hapten-specific T cell functions in response to altered antigenic ligands
ㆍFermentation of recombinant insulin analogue in Escherichia coli and its purification by affinity chromatography
ㆍ긴꼬리말불버섯(Lycoperdon pedicellatum) sarcoma 180에 대한 항암 • 면역활성
ㆍKlebsiella aerogenes의 UreF Fusion 단백질의 분리 , 정제 및 polyclonal antibody 제조에의 응용
ㆍPrediction of Warfarin maintenance dose from initial response in Korean cardiac valve surgery patients
ㆍTungsten-188/Rhenium-188 발생기의 정도관리
ㆍThe cytotoxicity and topoisomerase I inhibition of Rubus crategifolius extracts
ㆍMechanism of tamoxifen-induced apoptosis in human hepatoma cells
ㆍProtoberberine 계열 화합물이 P815 세포중의 serotonin 생합성 과정에 미치는 영향
ㆍBenzylisoquinoline 계열 화합물이 P815 세포중의 serotonin 생합성 과정에 미치는 영향
ㆍInhibitory effects of bulbocapnine on dopamine biosynthesis in PC12 cells
ㆍLow flow hypoxia model에서 Vitamin C의 용량에 따른 효과
ㆍ저산소 및 산소재도입시 저산소 모델에 따른 약물대사 효소계의 변동
ㆍOxytocin의 혈액-뇌관문 투과성과 약물동력학
ㆍ뇌질환 치료제의 개발 및 검색을 위한 약물의 뇌 투과 평가법
ㆍInhibition of the telomerase activity and catalytic subunit in human breast cancer cells by retionoids in vitro
ㆍInhibitory activity of 7-oxo-8(14), 15-pimaradiene-19-oic acid from Araliae cordatae root on immediate and late phase asthmatic responses in guinea pigs
ㆍInhibitory activity of l,2-bis[4-(β-D-glucopyranosyloxy)-benzyl] citrate from Gastrodiae root on immediate and late phase astmatic responses in guinea pigs
ㆍInhibitory activity of bergenin from Cimiifugae root on immediate and late phase asthmatic responses in guinea pigs
ㆍInhibitory activity of apigenin-7-O-D-glucopyranoside from Charaganae root on immediate and late phase asthmatic responses in guinea pigs
ㆍPharmacokinetics of indomethacin after intravenous administration to premature infants for prophylactic treatment
ㆍThe pharmaco-constituents of Korean cultivated Rhubarb Rhizomes (V)
ㆍStudy on anti-OHYUL activity of Rhubarb Ⅱ. Anti-allergic effects of stilbene components from Korean cultivated Rhubarb Rhizomes
ㆍ보양제에 속하는 생약의 항산화 효과
ㆍAraliaceae를 포함한 삼십여종 생약의 소염활성 연구
ㆍ야생인삼(人蔘)의 부견
ㆍ新생약자원(제3보) New Natural Drugs in Korea(Ⅲ)
ㆍ모델항원인 Ovalbumin을 함유하는 생분해성 미립자의 제조 및 특성
ㆍ폴록사머를 이용한 코지산 외용제의 제조 및 평가
ㆍThe development of new linker for alcohols and carbohydrates in solid-phase reaction
ㆍEfficient synthesis of 3-arylisoqumoline-1(2H)-ones and nucleophilic substitution in the reactions of arendiazonium cations with nitrile ion
ㆍ5-Aminosalicylic acid의 결장표적성 prodnig의 개발: 5-aminosalicyl-L-cysteine의 합성 및 성상
ㆍ5-Fluorouracil의 Prodmgs: N-Acyl-2-(5-fluorouracil-1-yl)-D,L-glycine의 합성 및 성상
ㆍH-ras와 N-ras가 도입된 Human Breast Epithelial Cell에 Capsaicin이 미치는 영향에 관한 연구
ㆍH-ras에 외해 유도되는 침윤성 증가에 있어서의 Matrix Metalloproteinses (MMPs)의 세포특이적 발현