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홈 > 간행물 권호
  • 발행기관: 대한갑상선-내분비외과학회
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The Koreran journal of Endocrine Surgery(The Koreran journal of Endocrine Surgery)

  • 발행기관 : 대한갑상선-내분비외과학회(The Korean Association of Endocrine Surgeons)
  • 출처구분 : 학회
  • 간행물유형 : 학술저널
  • 발행주기 : 계간 (발행월:3,6,9,12)
  • pISSN : 1598-1703
  • eISSN : 2287-6782
  • 등재정보 : KCI 등재
The Koreran journal of Endocrine Surgery
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Which Clinicopathological Factors Are Related to Tumor Size in Papillary Thyroid Cancer?
Which Clinicopathological Factors Are Related to Tumor Size in Papillary Thyroid Cancer?
Sunseok Yoon;Jeonghun Lee;EuyYoung Soh
대한갑상선-내분비외과학회 / 대한내분비외과학회지19권4호 / 2019 / 95-105 (11 pages)
의약학>일반외과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 일반외과학
초록보기
Purpose: Papillary thyroid cancer (PTC) is the most common endocrine cancer worldwide. Tumor size on observation, together with lymph node metastasis, serves as a determinant of surgery. However, not all patients with PTC experience an increase in the size of tumor. We investigated various clinicopathological factors associated with the size of tumor to discern the group that can be observed without the need for early surgery. Methods: The records of 1,401 patients diagnosed with PTC (excluding the follicular variant) between 2015 and 2017, were reviewed. Clinicopathological features suspected to have a link to tumor growth were included, such as diabetes mellitus (DM), use of metformin, a surgical history of breast, ovary, uterine, or familial non-medullary thyroid cancer, B-type Raf kinase (BRAF) V600E mutation, and lymphovascular invasion (LVI). Results: Size of tumor was found to be related to sex, age, hypertension, ovary-uterine surgery, LVI and psammoma bodies. However, after adjusting for the effects of other factors on tumor size, both age and LVI were found to be significantly related to tumor size, with age also being significantly related to LVI. Conclusion: Age and LVI are significant factors in the enlargement of tumors, unlike several other features, including DM, breast cancer history, familial cancer history, Graves s disease, Hashimoto s thyroiditis, and BRAF mutation.
A Prospective, Randomized, Controlled Comparative Study of Three Energy Devices in Open Thyroid Surgery: Thunderbeat, Harmonic, and Ligasure
A Prospective, Randomized, Controlled Comparative Study of Three Energy Devices in Open Thyroid Surgery: Thunderbeat, Harmonic, and Ligasure
Kyorim Back;Nayoon Hur;Min Jhi Kim;Jun-Ho Choe;Jung-Han Kim;Jee Soo Kim
대한갑상선-내분비외과학회 / 대한내분비외과학회지19권4호 / 2019 / 106-115 (10 pages)
의약학>일반외과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 일반외과학
초록보기
Purpose: Energy devices, such as Harmonic Focus Plus (Ethicon; ultrasonic scalpel; Harmonic) and Ligasure Small Jaw (Covidien; bipolar sealer; Ligasure) are widely used in thyroid surgery as substitutes for Bovie (electrocautery) and sutures. They reduce operation time and peri-operative complications. Thunderbeat Open Fine Jaw (Olympus; Thunderbeat) is a recently developed energy device, which combines the functions of both ultrasonic scalpel and bipolar sealer. We prospectively evaluated the safety and feasibility of Thunderbeat during open thyroidectomy compared with Harmonic and Ligasure. Methods: From September to November 2016, patients with papillary thyroid cancer or benign thyroid disease who underwent unilateral or bilateral thyroidectomy at Samsung Medical Center were enrolled. Thyroidectomies were performed by a single surgeon who specializes in endocrine surgery and is experienced in using energy devices. The patients were randomly allocated to one of the 3 groups according to the energy device used during the operation: Harmonic, Ligasure, and Thunderbeat group. Results: No significant differences were detected among the 3 groups in intra-operative bleeding, drainage amount, incidence of transient hypocalcemia, and transient vocal cord palsy. The surgical time for thyroidectomy in the T group was shorter than in the other 2 groups (P=0.031). However, the H group showed reduced surgical time for central lymph node dissection. Conclusion: Among the 3 energy devices, Thunderbeat and Harmonic shortened the surgical time for thyroidectomy and central lymph node dissection, respectively. However, each energy device has its own strengths and weaknesses, and we recommend the selection of devices based on the respective features.
Relationship between Initial Thyroid Operation and the Location of Locoregional Recurrence in Papillary Thyroid Cancer: a Single Tertiary Center Experience
Relationship between Initial Thyroid Operation and the Location of Locoregional Recurrence in Papillary Thyroid Cancer: a Single Tertiary Center Experience
Choong Sil Rah;Jin Gi Chang;Won Woong Kim;Yu-mi Lee;Min Ji Jeon;Dong Eun Song;Young Jun Choi;Ki-Wook Chung;Suck Joon Hong;Tae-Yon Sung
대한갑상선-내분비외과학회 / 대한내분비외과학회지19권4호 / 2019 / 116-125 (10 pages)
의약학>일반외과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 일반외과학
초록보기
Purpose: Locoregional recurrence of papillary thyroid cancer (PTC) after initial thyroid operation is frequent in high-risk patients. However, many studies have reported on risk factors for recurrence without presenting the actual location or patterns of these recurrences. We evaluated the efficacy of initial thyroid operation, which could affect the location of recurrence and prognosis of PTC, thereby requiring reoperation. Methods: This was a retrospective observational cohort study of patients undergoing initial thyroidectomy for PTC with recurrences during follow-up at a single tertiary center. Results: In total, 210 (12.8%) first recurrences and 23 (1.4%) second recurrences were detected after the initial thyroid operation. Recurrences occurred mostly after total thyroidectomy (TT) with central compartment node dissection (CCND) (51.5%) and TT with lateral neck node dissection (LND) (27.5%). The most frequent site of the first locoregional recurrence was the lateral neck node area at the non-operated site of the initial thyroid operation (67.1%). Among patients with a second recurrence, 91.3% had a first recurrence within 5 years after operation. Conclusion: Patients receiving TT with CCND or TT with LND should undergo a thorough examination of lateral neck node area during follow-up, especially at the non-operated lateral neck site. In addition, close observation for a second recurrence is needed for patients with a first recurrence in the early years after the initial operation.
Changing Trends in Preoperative Localization and Surgical Techniques for the Treatment of Primary Hyperparathyroidism in a Single Tertiary Center
Changing Trends in Preoperative Localization and Surgical Techniques for the Treatment of Primary Hyperparathyroidism in a Single Tertiary Center
Jumyung Lee;Su-jin Kim;Hyeong Won Yu;Young Jun Chai;June Young Choi;Kyu Eun Lee
대한갑상선-내분비외과학회 / 대한내분비외과학회지19권4호 / 2019 / 126-135 (10 pages)
의약학>일반외과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 일반외과학
초록보기
Purpose: Primary hyperparathyroidism (PHPT) is caused by the oversecretion of parathyroid hormone (PTH), resulting in increased serum calcium levels. The aim of this study was to analyze changing trends in preoperative localization and surgical techniques for the treatment of PHPT in a single tertiary center in Korea. Methods: Data from patients with PHPT who had undergone parathyroidectomy between January 2000 and December 2016 were evaluated in this retrospective analysis. Results: Data from 157 patients were included in this analysis (single adenoma n=156, double adenoma n=1). A total of 134 patients underwent ultrasonography for preoperative localization, 110 of which were marked preoperatively. Preoperative localization by sonographic marking increased over time following its introduction in 2006. Intraoperative PTH assay was used in 80 patients, with its use also increasing each year since it was introduced in 2011. In addition, 150 patients underwent 99mTc-sestamibi scan and 148 underwent computed tomography (CT) scanning. Four-dimensional CT and 99mTc-sestamibi SPECT/CT (SeS) was introduced in 2011 and replaced the use of 2-dimensional CT and 99mTc-sestamibi scan over time. Statistical analysis revealed that sonographic marking, SeS, CT, intraoperative PTH significantly reduce operation time. Surgical techniques used were bilateral neck exploration (n=11), unilateral neck exploration (n=54), focused parathyroidectomy (n=84), and others (n=8). Among 5 surgical technique, focused parathyroidectomy took significantly lesser operation time than other surgical methods. Conclusion: In order to reduce operation time, sonographic marking, SeS, CT, intraoperative PTH should be performed perioperatively, and focused parathyroidectomy could be the first choice of surgical methods.
The Incidence and Clinicopathologic Characteristics of Patients Who Had False-Positive Fine-Needle Aspiration Results for Papillary Thyroid Cancer
The Incidence and Clinicopathologic Characteristics of Patients Who Had False-Positive Fine-Needle Aspiration Results for Papillary Thyroid Cancer
Yoonju Bang;Kyorim Back;Jung-Han Kim;Junho Choe;Jee Soo Kim
대한갑상선-내분비외과학회 / 대한내분비외과학회지19권4호 / 2019 / 136-143 (8 pages)
의약학>일반외과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 일반외과학
초록보기
Purpose: Fine needle aspiration (FNA) is a well-established method for diagnosis of thyroid tumors. However, FNA sometimes fails to distinguish benign thyroid nodules from papillary thyroid carcinoma (PTC). The aim of this study was to evaluate the incidence and clinicopathologic characteristics of patients who had thyroidectomy due to consistent findings of PTC in FNA but turned out to bear no evidence of malignancy in surgically removed thyroids. Methods: We retrospectively reviewed 10,776 patients who underwent thyroid surgery from January 2009 to January 2019 due to suspicion for PTC, 40 of whom were diagnosed as benign in final histology. Results: We compared the clinical and pathologic characteristics of 2 groups, including subgroup analysis between Bethesda category V and VI. The false(+) rate for FNA was 0.4%. The ratio of patients aged ≥55 years was statistically higher in the false(+) group compared to the true(+) group. Age ≥55 years and Bethesda category V were risk factors for false(+) FNA in multivariate analysis. Conclusion: Although the false(+) rate is low (0.4%), surgeons should be aware of these circumstances and inform patients of the possibility of a false positive result in those with age >55 years, suspicion for malignancy on FNA (Bethesda category V), and low suspicion/benign for Korean thyroid imaging reporting and data system. To reduce unnecessary thyroidectomy, core needle biopsy or repeat FNA should be considered for a patient with these findings. Further large-scale studies are necessary to establish a firm conclusion.
What You Need to Know about Mental Nerve Surgical Anatomy for Transoral Thyroidectomy
What You Need to Know about Mental Nerve Surgical Anatomy for Transoral Thyroidectomy
Antonella Pino;Andrea Parafioriti;Ettore Caruso;Maria De Pasquale;Paolo Del Rio;Pietro Giorgio Calò;Gianlorenzo Dionigi;Francesco Stagno d Alcontres
대한갑상선-내분비외과학회 / 대한내분비외과학회지19권4호 / 2019 / 144-150 (7 pages)
의약학>일반외과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 일반외과학
Venous Thromboembolism Following Thyroid Surgery
Venous Thromboembolism Following Thyroid Surgery
Özer Makay;Hui Sun;Alessandro Pontin;Ettore Caruso;Antonella Pino;Tommaso Mandolfino;Gianlorenzo Dionigi
대한갑상선-내분비외과학회 / 대한내분비외과학회지19권4호 / 2019 / 151-153 (3 pages)
의약학>일반외과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 일반외과학
초록보기
Venous thromboembolism is viewed as a serious health care issue. Patients who experience venous thromboembolism often have an detoriorated quality of life after the event that may require anticoagulation. This results to the risks of spontaneous bleeding. Bleeding after thyroid surgery can present acutely and can lead to airway compromise and death if not recognized and treated appropriately. Whether prophylaxis in a low-risk patient puts the patient at a greater risk of developing a bleeding complication is not well documented. The literature is scarce regarding the prevalence of venous thromboembolism following thyroid and parathyroid surgery.
Efficacy of Percutaneous Thermal Ablation of Papillary Thyroid Carcinoma
Efficacy of Percutaneous Thermal Ablation of Papillary Thyroid Carcinoma
Ettore Caruso;Ettore Gagliano;Gianlorenzo Dionigi
대한갑상선-내분비외과학회 / 대한내분비외과학회지19권4호 / 2019 / 154-156 (3 pages)
의약학>일반외과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 일반외과학
초록보기
Percutaneous thermoablation (PTA) has become an increasingly used option in the interventional treatment of symptomatic, cytologic and sonographic benign solid thyroid gland disease. Currently, there is no high-level evidence of treatment for differentiated thyroid cancer by means of PTA. Surgery is a standard treatment for primary and also for recurrent thyroid cancer, followed by radioactive iodine and thyroid hormone therapy. PTA, however, can be used in patients at high-risk and in patients who refuse to undergo repeated surgery. The Task Force Committee of the Korean Society of Thyroid Radiology has developed recommendations for the optimal use of PTA for thyroid nodules. However, there are still several questions on safe distance to the laryngeal nerves, no data on duration of PTA application around the nerves, no intra-procedure assessment of laryngeal nerves function and position. Future experimental studies are required.
Preoperative Treatment with Lugol Solution for Graves  Disease
Preoperative Treatment with Lugol Solution for Graves Disease
Özer Makay;Hui Sun;Ettore Caruso;Antonella Pino;Alessandro Pontin;Tommaso Mandolfino;Gianlorenzo Dionigi
대한갑상선-내분비외과학회 / 대한내분비외과학회지19권4호 / 2019 / 157-158 (2 pages)
의약학>일반외과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 일반외과학
초록보기
Graves disease is one of the commonest causes of hyperthyroidism. Pre-treatment with Lugol solution, containing iodine/potassium iodide, to induce euthyroidism before surgery may be suggested, especially in case of adverse events due to antithyroid medication. Whether post-operative outcomes are any different following a course of Lugol solution in patient with Graves disease is not well-documented in the literature. It is definite that large, prospective, randomized controlled trials of clinical and scientific are warranted to answer whether or not preparation with Lugol solution is necessary prior to surgery for Graves disease.
Recommended Surgery for >1 cm Noninvasive Follicular Neoplasia with Papillary-Like Nuclear Features (NIFTP)
Recommended Surgery for >1 cm Noninvasive Follicular Neoplasia with Papillary-Like Nuclear Features (NIFTP)
Alessandro Pontin;Ettore Gagliano, Gianlorenzo Dionigi
대한갑상선-내분비외과학회 / 대한내분비외과학회지19권4호 / 2019 / 159-161 (3 pages)
의약학>일반외과학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 일반외과학
초록보기
Papillary thyroid carcinoma (PTC) is a heterogeneous tumor group with differing pathogenesis and prognosis of the individual subtypes. In addition, a tumor entity has been spun off, now referred to as “noninvasive follicular neoplasm with papillary-like nuclear features (NIFTP). A recent study, based on a comprehensive evaluation of a prospective multicenter NIFTP-based retrospective study, was intended to clarify whether NIFTP can metastasize and thus justify a reduced resection rate compared to classical PTC. For 3 reasons, Authors nicely recommend caution regarding a limited thyroid procedure (i.e. lobectomy vs. completion thyroidectomy): i) In the current literature, lymph node metastases have been described in 10 patients with NIFTP, and in 1 patient lung metastases. ii) As reported for the first time in this study, nearly one-fifth of patients have NIFTP-associated PTMC with unclear potential for metastasis. iii) Observation periods are still relatively short and so far, there are no agreed follow-up standards.