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  • 발행기관: 대한안과학회
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The Korean Journal of Ophthalmology(The Korean Journal of Ophthalmology)

  • 발행기관 : 대한안과학회
  • 출처구분 : 학회
  • 간행물유형 : 학술저널
  • 발행주기 : 계간
  • Print ISSN : 2092-9382
  • Online ISSN : 1011-8942
  • 등재정보 : KCI 등재
The Korean Journal of Ophthalmology
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14
Reattachment of Rhegmatogenous Retinal Detachment via Fibrin Tissue Adhesive
Reattachment of Rhegmatogenous Retinal Detachment via Fibrin Tissue Adhesive
Erdinc Aydin;Erdem Eris;Levent Kazanci;Osman Murat Uyar
대한안과학회 / Korean Journal of Ophthalmology Vol.35 No.3 / 2021 / 173-178 (6 pages)
의약학>기타의약학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 안과학
초록보기
Purpose: To manage reattachment of rhegmatogenous retinal detachment using tissue adhesive (fibrin glue) in five patients. Methods: Five eyes of five patients with rhegmatogenous retinal detachment were treated with 23-gauge pars plana vitrectomy and the application of fibrin glue (Tisseel Lyo) into the break under air without laser photocoagulation or cryopexy. Results: The median age of patients was 64 (range, 46–82) years, and the median duration of symptoms was 15 (range, 7–60) days. Three eyes had inferior and two had superior rhegmatogenous retinal detachments. Successful retinal reattachment was achieved in all cases and maintained during the followıng 10 to 24 months. The median best-corrected visual acuity improved from 2 / 100 preoperatively to a Snellen visual acuity of 20 / 50 by 6 months postoperatively. No postoperative complications were detected during the follow-up period. Conclusions: Excellent adhesive effects of fibrin glue with respect to sealing retinal tears with no side effects were seen in our study. With further prospective studies, this technique could be an alternative method to conventional retinopexy.
Acute and Chronic Ophthalmic Involvement, Severity, and Sequelae in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Acute and Chronic Ophthalmic Involvement, Severity, and Sequelae in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Sunil Ganekal;Ashwini Nagarajappa
대한안과학회 / Korean Journal of Ophthalmology Vol.35 No.3 / 2021 / 179-187 (9 pages)
의약학>기타의약학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 안과학
초록보기
Purpose: To study the ocular manifestations, its severity and sequelae in patients with Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). Methods: Prospective study of 44 consecutive patients (30 SJS and 14 TEN) presenting in the acute phase of the disease. Patients were evaluated by dermatologist as well as physician for systemic status, skin lesions and mucosal involvement. Detailed history taking, visual acuity, ophthalmic evaluation (lid margin, corneal, conjunctival changes, tear film and ocular surface). Ocular severity score (OSS) was assessed at baseline (acute) and at 6 months (chronic / OSS6), graded as mild, moderate and severe. Results: Mean age was 28.15 ± 15.78 years. Sixty-five eyes of 33 patients were included for final analysis. Thirty-eight patients (86.4%) had ocular manifestations. Drugs were the most common causative factor (95.4%). At base line mild, moderate, and severe OSS was seen in 43.1%, 44.6%, and 12.3% eyes. At 6 months mild, moderate, and severe OSS was seen in 44.6%, 7.7%, and 6.2% of eyes. There was a significant correlation between age of the patient and OSS at 6 months (p = 0.02). Younger age had higher chronic OSS. Patients with TEN had higher acute (p = 0.001) and chronic (p = 0.001) OSS than SJS. Three mucosal surface involvement associated with higher acute and chronic OSS (p = 0.001). No long-term ocular complications observed in 27 / 65 (41.5%) eyes. Acute OSS correlated significantly with chronic OSS, at 1 and 6 months (p = 0.001). Conclusions: Greater severity of the disease, more number of mucosal surfaces involved and shorter symptom lag correlated with more severe acute and chronic ocular manifestations. The severity of lid margin involvement and corneal involvement in acute stage were good predictors of severity of chronic ocular findings. Initial severity of ocular involvement correlated with severity of ocular sequelae.
Comparison between 0.1% Nepafenac and 1% Prednisolone Eye Drop in Postoperative Management Following Micro-incisional Cataract Surgery
Comparison between 0.1% Nepafenac and 1% Prednisolone Eye Drop in Postoperative Management Following Micro-incisional Cataract Surgery
Sandip Sarkar;Narayan Bardoloi;Amit Kumar Deb
대한안과학회 / Korean Journal of Ophthalmology Vol.35 No.3 / 2021 / 188-197 (10 pages)
의약학>기타의약학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 안과학
초록보기
Purpose: To compare the efficacy of 0.1% nepafenac and 1% prednisolone acetate eye drop in postoperative inflammation control in micro-incisional cataract surgery. Methods: We conducted a prospective, randomized, comparative, single-blind study. All the patients underwent temporal 2.2-mm micro-incisional cataract surgery. They were randomized into two groups (group A and B). Group A received 0.1% nepafenac eye drops 4 times/day for 4 weeks and group B received 1% prednisolone acetate eye drops in tapering doses for 4 weeks after surgery. Both the groups received moxifloxacin 0.5% eye drops 4 times/day for 2 weeks. Patients were examined on 1st, 7th, and 30th postoperative days and parameters of postoperative inflammation were evaluated and noted at each visit. Results: A total of 200 patients were enrolled in the study. However, five patients lost to follow up, group A had 97 and group B had 98 patients respectively. Results were statistically insignificant in terms of the difference in lid edema, conjunctival congestion, corneal edema, anterior chamber cells and flare between the two groups with p-values >0.05 for each parameter at each visit. However, the difference in mean central macular thickness between the groups was significant (205.713 ± 17.14 vs. 220.984 ± 32.83 in group A and B, respectively, p ≤ 0.001) at 1 month. Also, the mean pain score was significantly lower (p = 0.018) in the nepafenac group at day 7 of surgery. Conclusions: Nepafenac is equally effective and non-inferior to prednisolone acetate in suppression and prevention of inflammation in postoperative period.
Blood Count-derived Immunoinflammatory Markers in Thyroidassociated Ophthalmopathy
Blood Count-derived Immunoinflammatory Markers in Thyroidassociated Ophthalmopathy
Volkan Yeter;Nurullah Koçak;Mehmet Tayfun Arslan;Elif Kiliç Kan
대한안과학회 / Korean Journal of Ophthalmology Vol.35 No.3 / 2021 / 198-206 (9 pages)
의약학>기타의약학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 안과학
초록보기
Purpose: To investigate the diagnostic and prognostic significance of the blood-count derived systemic immunoinflammatory parameters in patients with thyroid-associated ophthalmopathy (TAO). Methods: In this retrospective case-control study, the blood-count parameters and neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio, and systemic immune-inflammatory index (SII), thyroid peroxidase antibody, and anti-thyroglobulin antibody were evaluated in 46 patients with TAO and 46 matched controls. The associations of the immunoinflammatory parameters with clinical outcomes were analyzed among TAO patients. Results: Significant differences were found in NLR, PLR, SII, and lymphocyte count between the controls and the TAO group (p < 0.05 for all). In logistic regression analysis, these inflammatory parameters did not have any prognostic effect on the clinical outcomes of the TAO (p > 0.05 for all). The patients, who needed systemic treatment due to any ocular involvement of TAO during the follow-up period, had significantly lower platelet count (p = 0.001) and PLR (p = 0.02) at the time of initial diagnosis when compared to the no treatment-needed group of the TAO patients. The initial platelet count was significantly associated with the subsequent steroid need due to TAO during the follow-up period (β = -0.02, p = 0.03). Conclusions: NLR, PLR, and SII may serve as potential inflammatory markers in the identification of the TAO, although they have no evident prognostic significance in TAO. However, the relatively lower platelet count at initial diagnosis may be associated with the need for systemic therapy during the follow-up in patients with TAO.
Atypical Retinal Hemorrhages after Vitrectomy for Idiopathic Macular Hole: Possible Toxicity of Brilliant Blue G
Atypical Retinal Hemorrhages after Vitrectomy for Idiopathic Macular Hole: Possible Toxicity of Brilliant Blue G
Jae Jung Lee;Seung Kwon Choi;Han Jo Kwon;Seung Min Lee;Sung Who Park;Ik Soo Byon;Ji Eun Lee
대한안과학회 / Korean Journal of Ophthalmology Vol.35 No.3 / 2021 / 207-214 (8 pages)
의약학>기타의약학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 안과학
초록보기
Purpose: To describe the development of multiple retinal hemorrhages after uncomplicated macular hole (MH) surgery, and to determine the associated factors. Methods: The medical records of 163 patients (167 eyes) diagnosed with idiopathic MHs and who underwent surgery at Pusan National University Hospital between March 2016 and July 2018 were retrospectively reviewed. The development of retinal hemorrhages was evaluated using ultra-widefield fundus photographs. Multiple retinal hemorrhages were defined as three or more dot or blot hemorrhages that had not been observed before and during the surgery. The patients were divided into two groups according to the presence of multiple retinal hemorrhages. The variable parameters were compared between the two groups to find the risk factors. The associated factors were evaluated further for the independent factor using multiple logistic regression analysis. Results: Multiple retinal hemorrhages were observed in 31 eyes (18.6%) after MH surgery. The associated factors were the surgical induction of posterior vitreous detachment (PVD) (p = 0.003), use of the internal limiting membrane flap technique (p = 0.028), and staining with Brilliant Blue G (BBG) (p = 0.003). Retinal hemorrhages were exclusively observed in eyes in which BBG was used. Surgical PVD induction was the only independent risk factor (odds ratio, 13.099; p = 0.013). No statistically significant differences were observed between the two groups in the postoperative visual outcomes and MH closure rate. Additionally, patients who underwent surgery for idiopathic epiretinal membrane during the study period were reviewed to validate the above findings. Multiple retinal hemorrhages were noted in only one case (0.4%) in which BBG was used after surgical induction of PVD. Conclusions: Multiple retinal hemorrhages after MH surgery appear to be related to the intravitreal use of BBG in eyes that sustained mechanical damage because of surgical induction of PVD; however, they did not affect surgical outcomes.
Protective Role of 360° Laser Retinopexy in Patients with Rhegmatogenous Retinal Detachment: a Systematic Review and Meta-analysis
Protective Role of 360° Laser Retinopexy in Patients with Rhegmatogenous Retinal Detachment: a Systematic Review and Meta-analysis
Christa Soekamto;Edward R Chu;Daniel A Johnson;Jeong-Hyeon Sohn;Sepehr Bahadorani
대한안과학회 / Korean Journal of Ophthalmology Vol.35 No.3 / 2021 / 215-222 (8 pages)
의약학>기타의약학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 안과학
초록보기
Purpose: Visual impairment from retinal re-detachment could be debilitating. The aim of this review is to evaluate the role of 360° laser retinopexy on success rate of rhegmatogenous retinal detachment (RRD) repair by a meta-analysis study. Methods: The PubMed, Scopus, and the Cochrane Library databases were searched comprehensively from the date of database inception to January 2021, evaluating the role of 360° laser retinopexy in visual and anatomical success rate of RRD repair. This review was conducted based on the preferred reporting items for systematic review and meta-analysis (PRISMA) protocols. Results: Among 202 articles screened for eligibility, six studies were found to be eligible for inclusion in our final analysis. Our meta-analysis demonstrates that prophylactic treatment with circumferential laser photocoagulation has no significant effect on the initial rate of retinal re-detachment or final best-corrected visual acuity following pars plana vitrectomy repair of RRD. Subgroup analysis of studies (n = 3) with 23-gauge pars plana vitrectomy, however, favors attachment rate in patients undergoing 360° prophylactic laser treatment. Conclusions: Three hundred and sixty degree laser retinopexy appears to have favorable outcomes in patients undergoing 23-gauge retinal detachment repair. This protective effect, however, is not apparent with inclusion of 20-gauge vitrectomy studies.
Evaluation of Retinal Nerve Fiber Layer Thickness and Optic Nerve Head Parameters in Obstructive Sleep Apnoea Patients
Evaluation of Retinal Nerve Fiber Layer Thickness and Optic Nerve Head Parameters in Obstructive Sleep Apnoea Patients
Qi Zhe Ngoo;Nazihatul Fikriah A;Baharudin A;Wan Hazabbah WH
대한안과학회 / Korean Journal of Ophthalmology Vol.35 No.3 / 2021 / 223-230 (8 pages)
의약학>기타의약학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 안과학
초록보기
Purpose: To study the retinal nerve fiber layer (RNFL) thickness and optic nerve head (ONH) parameters in obstructive sleep apnoea (OSA) patients and their relationship with severity of the disease. Methods: A cross-sectional, hospital-based study. Fifty-four OSA subjects and 54 controls were recruited. Candidate that fulfil the criteria with normal ocular examinations then proceed with spectrum domain Cirrus optical coherence tomography examinations. ONH parameters and RNFL thickness were evaluated. Apnoea-hypopnoea index (AHI) of the OSA group were obtained from the medical record. Results: In OSA, mean of average RNFL thickness was 93.87 μm, standard deviation (SD) = 9.17, p = 0.008 (p < 0.05) while superior RNFL thickness was 113.59 μm, SD = 16.29, p ≤ 0.001 (p < 0.05). RNFL thickness fairly correlate with severity of the disease (AHI), superior RNFL with R = 0.293, R2 = 0.087, p = 0.030 (p < 0.05), and nasal RNFL R = 0.292, R2 = 0.085, p = 0.032. No significant difference and correlation observed on ONH parameters. In control group, mean of average RNFL thickness was 98.96 μm, SD = 10.50, p = 0.008 (p < 0.05) while superior RNFL thickness was 125.76 μm, SD = 14.93, p ≤ 0.001 (p < 0.05). Conclusions: The mean of the average and superior RNFL thickness were significantly lower in the OSA group compare to control. Regression analysis showed RNFL thickness having significantly linear relationship with the AHI, specifically involving the superior and nasal quadrant.
Successful Reposition of Prolapsed Silicone Tube Using Hole and Lacrimal Probe Method
Successful Reposition of Prolapsed Silicone Tube Using Hole and Lacrimal Probe Method
Zee Yoon Byun;Bo Ram Lee;Sung Chul Kim
대한안과학회 / Korean Journal of Ophthalmology Vol.35 No.3 / 2021 / 231-234 (4 pages)
의약학>기타의약학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 안과학
초록보기
Purpose: Silicone tube intubation is the most common method for treatment of nasolacrimal drainage disorder or repair of lacerated canaliculus. However, some cases are prolapsed earlier than expected, subsequently affecting the success rate of silicone tube intubation. The author introduced a successful reposition of the prolapsed silicone tube. Methods: This study is a retrospective case series of 11 patients who were treated with reposition of prolapsed silicone tube using hole and lacrimal probe method. In all cases, the tubes were prolapsed within 2 months after the first surgery due to careless rubbing of the medial canthus by the patient. In all 11 cases, the development of a biofilm on tube was not observed at the time when the tube was prolapsed. All patients underwent immediate reposition of prolapsed tube without local anesthesia in the outpatient operating room on the day they visited. Results: In all 11 cases, the prolapsed silicone tube was repositioned without any complications using this hole and lacrimal probe method. At 6-month follow-up examination, all patients presented with a well-positioned silicone tube up to the day of extubation without replacing it with a new silicone tube. Conclusions: This hole and lacrimal probe method is effective for the repositioning of prolapsed silicone tube after bicanalicular intubation of lacrimal system. This procedure includes easy performance in a short time and without local anesthesia in the outpatient operating room.
Efficacy and Safety of Preservative-free Latanoprost Eyedrops Compared with Preserved Prostaglandin Analogues in Patients with Open-angle Glaucoma
Efficacy and Safety of Preservative-free Latanoprost Eyedrops Compared with Preserved Prostaglandin Analogues in Patients with Open-angle Glaucoma
Hyo Jin Seong;Kwanghyun Lee;Seung Jae Lee;Sangah Kim;Jong Woon Park
대한안과학회 / Korean Journal of Ophthalmology Vol.35 No.3 / 2021 / 235-241 (7 pages)
의약학>기타의약학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 안과학
초록보기
Purpose: To evaluate the safety and efficacy of preservative-free (PF) latanoprost in glaucoma patients. Methods: In this prospective, open-label, observational study, a total of 27 primary open-angle glaucoma patients who used benzalkonium chloride-preserved prostaglandin analogues for at least 6 months were enrolled. After changing the eye drops to PF lataprost, the intraocular pressure (IOP) and ocular surface symptoms and signs were evaluated in all patients on days 0 (first visit, D0), 45 (D45), and 90 (D90). Results: Mean IOP remained stable during the study period (14.0 ± 2.4 mmHg at D0, 13.9 ± 2.0 mmHg at D45, 13.7 ± 2.2 mmHg at D90; p = 0.603). Mean deviation, pattern standard deviation, and best-corrected visual acuity were similar before and after eye drops replacement. Bulbar conjunctival hyperemia, corneal staining, and conjunctival staining were significantly decreased over 90 days (p = 0.025, p < 0.001, p = 0.020, respectively). The ocular surface disease index score showed a statistically significant improvement from 26.4 ± 18.5 at D0 to 19.8 ± 17.0 at D45 and 15.7 ± 15.6 at D90 (p < 0.001). In the evaluation of ocular tolerability, burning symptoms and dryness were significantly decreased (p = 0.001, p = 0.040). Conclusions: The effects of PF latanoprost on reducing IOP were comparable with those of benzalkonium chloride-preserved prostaglandin analogues, but side effects on the ocular surface were much less pronounced when PF latanoprost was used. With this efficacy, PF latanoprost could slow the progression of glaucoma by increasing patient compliance.
Use of Nd: YAG Laser to Recanalize XEN Gel Stent Occluded by Iris Pigment
Use of Nd: YAG Laser to Recanalize XEN Gel Stent Occluded by Iris Pigment
Jae Gon Kim;Chong Eun Lee
대한안과학회 / Korean Journal of Ophthalmology Vol.35 No.3 / 2021 / 242-243 (2 pages)
의약학>기타의약학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 안과학
Isolated Unilateral Tessier Cleft 10 with Anterior Staphyloma
Isolated Unilateral Tessier Cleft 10 with Anterior Staphyloma
Deepsekhar Das;Aishwarya Rathod;Saloni Gupta;Sujeeth Modaboyina;Sahil Agrawal
대한안과학회 / Korean Journal of Ophthalmology Vol.35 No.3 / 2021 / 244-245 (2 pages)
의약학>기타의약학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 안과학
Severe Acute Allergic Response to Intraorbital Polymethylmethacrylate Implant
Severe Acute Allergic Response to Intraorbital Polymethylmethacrylate Implant
Sonia Phulke;Navya Naveen Kalra;Uma Handa;Subina Narang
대한안과학회 / Korean Journal of Ophthalmology Vol.35 No.3 / 2021 / 246-247 (2 pages)
의약학>기타의약학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 안과학
Macular Hole Formation Following Vitrectomy for Ruptured Retinal Arterial Macroaneurysm
Macular Hole Formation Following Vitrectomy for Ruptured Retinal Arterial Macroaneurysm
Jae Hong An;Ji Hye Jang
대한안과학회 / Korean Journal of Ophthalmology Vol.35 No.3 / 2021 / 248-250 (3 pages)
의약학>기타의약학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 안과학
Recurrent Enterococcus faecalis Endophthalmitis Following Uneventful Cataract Surgery
Recurrent Enterococcus faecalis Endophthalmitis Following Uneventful Cataract Surgery
Tomas Bro;Otto Fricke;Per Montan
대한안과학회 / Korean Journal of Ophthalmology Vol.35 No.3 / 2021 / 251-253 (3 pages)
의약학>기타의약학 / KDC : 기술과학 > 의학 / KCI : 의약학 > 안과학